Infection Flashcards
Beta lactam antibiotics A- examples indications
A) Penicillins
- Amoxicillin - oral infections, Lyme disease, anthrax, H.pylori
- Co-amoxiclav - LRTIs, joint or bone infections, animal bites, GU
- BenPen
- Flucloxacillin
Beta lactam A antibiotic SEs
GI disturbance
Type I and IV hypersensitivity reactions
Cholestatic jaundice associated with co-amoxiclav use
Quinolones example and indication
Ciprofloxacin
Gram negative and gram positive bacteria including pseudomonas, chlamydia, gonorrhoea and typhoid
Beta lactam B - example and indications
2) Cephalosporins
- Cefotaxime - septicaemia, pneumonia’s biliary tract infections, meningitis, epiglottitis, gonorrhoea
Beta lactam B e.g. Cefotaxime SEs
10% cross over hypersensitivity risk if penicillin allergic
High c.diff risk
Quinolones e.g. Ciprofloxacin SEs
Tendon rupture esp in elderly Decreased seizure threshold Peripheral neuropathy Hypoglycaemia High C diff risk
Macrolides examples and indications
Clarithromycin
Similar spectrum to penicillins and atypical pneumonia’s and campylobacter
Macrolides e.g. Clarithromycin SEs
QT prolongation
SJS/TEN
Aminoglycosides example and indications
Gentamicin
Septicaemia secondary to gram negative and some gram positive organisms
Gentamicin SEs
Narrow therapeutic index
Nephrotoxicity and ototoxicity
Nitrofurantoin indication
UTIs
Nitrofurantoin SEs
Pulmonary fibrosis
Retroperitoneal fibrosis
Peripheral neuropathy
Trimethoprim indications
UTIs
Bronchitis
PCP
Trimethoprim SEs
Hyperkalaemia
Vancomycin indications
Gram positive cocci
C.diff (oral)
