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Core Meds > Malignant & Metabolic Disease > Flashcards

Malignant & Metabolic Disease Flashcards

1
Q

Anti-oestrogens

  • Example
A

Tamoxifen

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2
Q

Anti-oestrogens (tamoxifen)

  • Indication
A

ER-positive breast cancer

Anovulatory infertility

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3
Q

Anti-oestrogens (tamoxifen)

-side effects

A
  • increased endometrial changes
  • flushes
  • PV bleeding
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4
Q

Bisphosphonates

-examples

A

Alendronic acid, zolendronic acid, ibandronic acid

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5
Q

Bisphosphonates

-indication

A
  • treatment of osteoporosis

- prevention of steroid induced osteoporosis

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6
Q

Bisphosphonates

-Mode of action

A

Osteoclasts inhibitors (slows the rate of bone turnover)

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7
Q

Bisphosphonates

-side effects

A
  • oesophagitis
  • dyspepsia
  • GI upset
  • Atypical femoral fractures
  • Osteonecrosis of the jaw
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Core Meds (12 decks)

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