Infection in Pregnancy

Question 1

How does CMV present in immunocompetent patients?

Answer 1

Asymptomatic

or mild flu-like illness

Question 2

How does mononucleosis syndrome present?

Answer 2

Fever
Splenomegaly
Impaired liver function

Question 3

How is CM investigated?

Answer 3

Serology for CMV IgM and IgG

Question 4

What is the recommended treatment for pregnant women with CMV?

Answer 4

None (assuming immunocompetence)

Question 5

How may foetal CMV be diagnosed?

Answer 5

Amniocentesis

Question 6

What do babies with CMV tend to develop?

Answer 6

Sensorineural hearing loss
Psychomotor development delay
Visual impairment

Question 7

What are the risk factors for group B strep infection in the baby?

Answer 7

Prematurity
Rupture of membranes >24hrs before delivery
Pyrexia during labour

Question 8

How may group B strep infection manifest in mother?

Answer 8

UTI
Chorioamnionitis
Endometritis

Question 9

How does chorioamnionitis present?

Answer 9

Fevers
Lower abdo and uterine tenderness
Discharge
Foetal tachycardia

Question 10

How does endometritis present?

Answer 10

Fevers
Lower abdo pain
Intermenstrual bleeding
Foul discharge

Question 11

How is group B strep infection diagnosed?

Answer 11

Vaginal and rectal swab

Urine culture

Question 12

How is group B strep infection treated?

Answer 12

Penicillin

Question 13

What prophylaxis is given to pregnant women who have risk factors for group B strep?

Answer 13

Penicllin

Question 14

What can parovirus 19 cause if transmitted to foetus?

Answer 14

Miscarriage

Intra-uterine death

Question 15

How does parovirus in adults tend to present?

Answer 15

Asymptomatic

Maybe symmetrical arthalgia

Question 16

How does parovirus 19 present in kids?

Answer 16

URTI
Malaise
Headaches
Fever
Erythema infectiosum

Question 17

What is erythema infectiosum?

Answer 17

Maculopapular rash sparing nose, eyes and mouth

Slapped cheek syndrome

Question 18

What is the most common manifestation of foetal parovirus 19?

Answer 18

Foetal hydrops

Question 19

Rubella vaccine cannot be given in pregnancy true/false

Answer 19

True - it is a live virus

Question 20

How does rubella present?

Answer 20

Asymptomatic

Non-specific - malaise, headache, rash, lymphadenopathy

Question 21

What kind of rash is found in rubella?

Answer 21

Fine maculopapular

Question 22

What is the risk of transferring rubella to the foetus before 12 weeks?

Answer 22

90%

Question 23

What is the likelihood of transferring rubella to the foetus over 20 weeks?

Answer 23

45%

Question 24

What is the classic rash found in varicella zoster infection?

Answer 24

Pruritic maculopapular rash

Question 25

What is the incubation period of varicella-zoster?

Answer 25

10-21 days

Question 26

When is the infectious period of varicella zoster?

Answer 26

48 hours prior to rash until vesicles crusted over

Question 27

What can a pregnant woman who comes into contact with varicella zoster be given prophylactically?

Answer 27

Varicella zoster immunogloublin

Question 28

What is given in varicella zoster infection in pregnancy?

Answer 28

Aciclovir

Question 29

What is the follow up to varicella zoster infection in pregnancy?

Answer 29

USS 5 weeks later (to check for foetal abnormality)