Infections

Question 1

Drug preparation ratio of sulfamethoxazole to trimethoprim to achieve maximum antibacterial action

Answer 1

5:1

Question 2

Mazzotti reaction. Which antihelminthic drug?

Answer 2

Ivermectin and diethylcarbamazepine

Question 3

Fever, urtucaria swollen lymph nodes tachycardia arthralgias abdominal pain that occur witn 7 days of treatment of microfilariasis. Treatment with ivermectin, diethylcarbamazepine.

Answer 3

Mazzotti reaction

Question 4

Binding to tubulin and inhibition of microtuble organization. Anti helminthic.

Answer 4

Mebendazole

Question 5

Drug of choice for schitosomiasis

Answer 5

Praziquantel

Question 6

Most common resistance for antibacterial medications

Answer 6

Beta lactamase inhibition

Question 7

Leprosy drug contraindicated in g6pd deficiency

Answer 7

Dapsone

Question 8

Cloramphenicol fatal idiosyncratic reaction. Rare.

Answer 8

Aplastic anemia

Question 9

Blood levels of penicillins can be increased by which drug

Answer 9

Probenicid

Question 10

Anti tb drug causing retrobulbar neuritis

Answer 10

Ethambutol

Question 11

Anti malarial drug used also in extra intestinal amoebiasis

Answer 11

Chloroquine

Question 12

Antifungal drug with excellent cns penetration

Answer 12

Fluconazole

Question 13

Antifungal drug for onychomycosis

Answer 13

Itraconazole

Question 14

First approved hiv drug

Answer 14

Zidovudine

Question 15

Methhemoglobinemia is common adverse effect of anti tb drug

Answer 15

Dapsone

Question 16

Used for tinea and onychomycosis but not candida onychomycosis

Answer 16

Griseofulvin

Question 17

Inhibits dihydropteorate synthesis. Antiparasitic drug

Answer 17

Sulfonamides

Question 18

Antiparasitic drug that is bioactivated to a cytotoxic pathway

Answer 18

Metronidazole

Question 19

Treatment for mrsa and hospital acquired infections

Answer 19

Vancomycin. But linezolid is more useful to hospital acquired infections

Question 20

Inhibits Dna dependent rna polymerase activity in bacterial cells

Answer 20

Rifampicin

Question 21

Anti staph drug poorly absorbed orally and with increased nephrotoxicity

Answer 21

Bacitracin

Question 22

Blocks peptidyltransferase by bInding in 50s subunit of bacterial ribosomes

Answer 22

Chlorampenicol

Question 23

Anti malarial drug which is a solely blood schizontizoide that causes dose dependent drug toxicity

Answer 23

Quinine

Question 24

Mild clostridium difficile infection. Metronidazole is given via

Answer 24

Orally