Infectious Disease Flashcards

1
Q

Gram positive bacteria definition

A

Have a thick peptidoglycan cell wall
Will stain with crystal violet stain

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2
Q

what type of bacteria can amoxicillin be used for

A

streptococcus (pneumococcus)
staphylococcus
oral anaerobes
haemophilus

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3
Q

amoxicillin allergy

A

give doxycycline/macrolide (clarithromycin)

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4
Q

what is flucoxacillin used for

A

staphylococcus infections
skin (cellulitis)
bone (osteomyelitis)

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5
Q

Cellulitis

A

Infection of the dermis and subcutaneous tissue
Presents with:
Warm, erythematous, painful plaque
Not well demarcated

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6
Q

dry cough, constipation, abdominal distension, increased bowel sounds, bradycardia, rose spots over torso
what is it? Ix?

A

typhoid
bone marrow aspirate

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7
Q

swollen cheeks, swollen painful testicles, meningitis/encephalitis

A

mumps

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8
Q

how does prion disease present

A

dementia
worsening cognitive impairment
myoclonus
cortical blindness

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9
Q

whipple’s disease Px

A

Multisystem disorder!!!!!
abdominal lymphadenopathy
iron deficiency anaemia
hyperpigmentation
cognitive decline

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10
Q

MONO
cause, px, dx, mx

A

Epstein barr virus
sore throat, fever, lymphadenopathy
monospot test
supportive Mx

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11
Q

lyme disease
cause, px, dx, mx

A

borellia
bulls eye rash (erythema migraines), fever
ELISA antibody test
doxycycline

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12
Q

rubella
cause, px, dx,

A

togavirus
fever, maculopapular rash that spares limbs, post auricular and sub occipital lymphadenopathy
dx: rubella specific IgM

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13
Q

creutzfeld-jakob disease
+ Dx

A

neurodegenerative prion infection
Dx on MRI

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14
Q

pregnant, exposed to chicken pox, asymptomatic

A

check varicella Immunoglobulins
administer Ig if they don’t have

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15
Q

pregnant, has chicken pox

A

aciclovir

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16
Q

kaposis sarcoma Px and cause
q

A

caused by human herpes 8
purple lesions over body

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17
Q

Farmer, weight loss, swollen joints
??? And Mx

A

Whipples disease
One year of co trimoxazole

18
Q

presentation of creutzfled jakob disease

A

progressive worsening dementia with myoclonic jerks

19
Q

2 features of measles + Mx

A

white koplik spots
macular rash
self resolving

20
Q

Group a strep causes

A

Rheumatic fever
Tonsillitis
Scarlet fever

21
Q

Group b strep causes

A

Septic abortion

22
Q

Morphology of c diff

A

Gram positive rod

23
Q

Abx for shigella 1st and 2nd line

A
  1. Ciprofloxacin 1 day
  2. Azithromycin 3 days
24
Q

2 features of scarlet fever, association, Mx

A

sandpaper rash
strawberry rash
assoc w Strep A
phenoxymethylpenicillin 10 days

25
Q

congenital rubella syndrome triad

A

deafness
blindness
PDA / congenital heart disease

26
Q

rubella 2 features and Mx

A

mild macular rash
post auricular and sub occipital lymphadenopathy
self resolving

27
Q

parvovirus b19 2 features and mx

A

slapped cheek rash
reticular rash on trunk
self resolving

28
Q

roseola infantum 2 features, Mx, complication

A

very high fever
mild macular rash

self resolving

febrile convulsions

29
Q

Px of cholera

A

secretory diarrhoea
hypovolemia
otherwise asymptomatic

30
Q

Dx of cholera

A

dark field microscopy of perianal swab
TCBS agar (grows yellow colonies overnight)

31
Q

cause of cholera

A

vibrio cholerae

32
Q

Mx of cholera

A

fluid replacement
ciprofloxacin

33
Q

diphtheria PX

A

exotoxin from the bacteria disrupts neuro supply of palate and hypopharynx → Paralysis + obstruction of larynx

Myocarditis

Peripheral neuropathy

34
Q

diphtheria Mx

A

Penicillin

isolation

cardiac monitor

35
Q

giardiasis Px

A

interferes with enteric brush border

watery diarrhoea, bloating, vomiting

abdo pain

steatorrhoea

chronic malabsoprtion

36
Q

giardiasis Dx

A

Stool antigen

cultures

37
Q

giardiasis Mx

A

metronidazole

38
Q

what organism is assoc with aspiration pneumonia

A

klebsiella pneumonia

39
Q

what organism is assoc with COPD exacerbation

A

haemophilus influenza

40
Q

what organism causes rust coloured sputum in pneumonia

A

strep pneumoniae

41
Q

Morphology of strep pneumoniae

A

Gram positive diplococcus

42
Q

Morphology of neisseria meningitides

A

Gram negative