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AMK > Renal > Flashcards

Renal Flashcards

1
Q

most common nephrotic syndrome in children

A

minimal change disease

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2
Q

Mx of minimal change

A

steroids

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3
Q

IgA nephropathy

A

Bergers sydnrome
Nephritic syndrome 1-2 days after a URTI

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4
Q

Post strep glomerulonephritis

A

Nephritic syndrome 1-2 weeks after URTI

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5
Q

goodpastures

A

Anti GBM antibodies against type 4 collagen
Px: heaemoptysis (lung haemorrhage) + nephritic syndrome

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6
Q

Alports

A

defect in gene for type 4 collagen
Px: renal failure, hearing loss, retinitis pigmentosa

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7
Q

renal biopsy in alports

A

splitting of the lamina dense shows a basket weave appearance

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8
Q

haemolytic uremic syndrome

A

caused by shiga toxin ( e coli 0157 / shigella)
AKI + thrombocytopenia + haemolytic anaemia)

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9
Q

henoch schlonhein purpura

A

abdominal pain
arthalgia
non-blanching rash

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10
Q

Granulomatosis with polyangiitis / wegener’s

A

URT = saddle shaped nose deformity, epistaxis

LRT = haemoptysis

Renal failure

cANCA!!!!!!

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11
Q

Churg strauss (eosinophilic granulomatosis and polyangitis)

A

Asthma

Rash

Renal failure

pANCA!!!!!!!

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12
Q

pain radiating from loin to groin

A

renal stones

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13
Q

what drugs cause AKI

A

diuretics, aminoglycosides, metformin, NSAIDs, lithium, ACEis, ARBS, digoxin

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14
Q

fever, uncontrollable shaking, flank/abdominal tenderness
gas in the renal parenchyma

A

pyelonephritis

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15
Q

antibiotics of choice for UTI in pregnancy

A

nitrofurantoin

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16
Q

acute tubular necrosis is caused by:

A

drugs (aminoglycosides, NSAIDs), radiocontrast

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17
Q

acute interstitial nephritis is caused by:

A

hypersensitivity, rheumatological conditions

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18
Q

Mx of pyelonephritis

A

IV gentamicin / ciprofloxacin

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19
Q

muddy brown casts

A

acute tubular necrosis

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20
Q

indications of acute dialysis

A

AEIOU
acidosis (<7.2)
electrolyte abnormalities (refractory hyperkalaemia)
intoxication e.g. alcohol, lithium
overload (fluid)
uremia (encephalopathy)

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21
Q

chronic reflux nephropathy

A

kidney scarring resulting from vesico-ureteric reflux

chronic UTIs in childhood
scarring and reduced size in one kidney
raised creatinine and hypertension

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22
Q

gold standard Dx for kidney stones

A

CT KUB

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23
Q

pathophis of type 1,2,4 renal tubular acidosis

A

(Distal) Type 1 = cannot excrete H+

hypokalemia, severe acidosis

(Proximal) Type 2 = cannot absorb HCO3-

hypokalemia, less acidosis

Type 4 = reduced aldosterone function

hyperkalemia, no significant acidosis

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24
Q

fanconi syndrome

A

Fanconi Sydnrome = proximal tubule dysfunction leading to poor electrolyte absorption

hypokalemia, acidosis

proteinuria, glycosuria

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25
Q

persisten hypertension not responding to ACEi

A

renal artery stenosis
more common in older people

26
Q

testicular cancer markers (3)

A

AFP raised in non-seminoma
bHCG raised in non-seminona
pALP raised in seminoma

27
Q

diagnosis of acute tubular necrosis

A

muddy brown casts in urinalysis
fraction of excreted sodium >3%

28
Q

two types of ATN and causes

A

toxic: drugs e.g. aminoglycosides, bisphosphonates, myoglobin

ischaemic: renal artery stenosis, hypoperfusion

29
Q

more common form of PKD

A

autosomal dominant

30
Q

assoc with ADPKD

A

berry aneurysms in the circle of willis
hypertension
urinary sx
liver cysts
abdominal mass

31
Q

combo of immunosuppression after kidney transplant

A

tacrolimus
mycophenalate mofetil
prednisolone

32
Q

side effects of MMF

A

gastro, bone marrow suppression

33
Q

when is radiofrequency ablation done in renal cancer

A

non surgical stage 1/2

34
Q

when is partial nephrectomy done

A

stage 1

35
Q

when is radial nephrectomy done

A

stage 2/3

36
Q

when are immunomodulatory drugs given in renal cancer

A

stage 4 (metastasis)

37
Q

ideal dialysate

A

0 urea
0 creat
high bicarb
low K

38
Q

struvite stones

A

chronic UTIS

39
Q

calcium oxalate stones

A

fat malabsorption (crohns, pancreatic insufficiency)

40
Q

calcium phosphate stones

A

hypercalcemia, hyperparathyroidism

41
Q

cystine

A

cystinuria
autosomal recessive

41
Q

uric acid stones

A

hyperuricemia (gout)

42
Q

symptoms of acute tubulointerstitial nephritis

A

fever
eosinophilia
rash

43
Q

causes of renal papillary necrosis

A

sickle cell anaemia
diabetes mellitus
acute pyelonephritis
chronic paracetamol use

44
Q

indications of calcium gluconate vs insulin&dextrose

A

calcium glutamate is used for cardioprotection in hyperkalemia

insulin and dextrose used to lower potassium

need both!!!!!!

45
Q

pain relief for kidney stones 1st line

A

IM diclofenac

46
Q

Potter syndrome

A

Oligohydramnios and resultant pulmonary hypoplasia with in utero renal failure

47
Q

inheritance of Alports

A

X linked recessive (most)

48
Q

inheritance of Von Hippel Lindau

A

autosomal dominant

49
Q

medullary sponge kidney
cause, Px, Dx

A

cystic dilatation of the collecting tubules in the kidney
increased risk of UTIs and kidney stones
grape-like appearance on ultrasound

50
Q

irregular testicular mass lesion
bHCG and AFP are not elevated
what could it. be?

A

testicular seminoma

51
Q

what does albumin:creatinine test for?
who to test

A

protein in the urine
test all people with diabetes + everyone without diabetes but have GFR<60

52
Q

best initial screening investigation for renal hypertension

A

abdo duplex ultrasound

53
Q

management of kidney stones >2cm

A

percutaneous ureterolithotomy

54
Q

management of kidney stones <0.5cm

A

paracetamol
drink water
stone passes spontaneously within 1-3 weeks

55
Q

management of stones <2cm

A

extracorporeal shock wave lithotripsy

56
Q

management of cryptorchid testis

A

orchidectomy (remove it)

57
Q

square envelope shaped crystals are caused by…
+ what vitamin

A

calcium oxalate
vitamin c

58
Q

how to calculate osmolality

A

Serum osmolality is 2 x(Na) + Urea + glucose

59
Q

acute vs chronic rejection of kidney transplant

A

acute <6 months. fever, graft pain, sudden rise in creatinine

chronic >6months. gradual creatinine rise, fibrosis and tubular atrophy

AMK (29 decks)

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