Flashcards in Infectious Particles Deck (18)
What are viruses?
obligate intracellular parasites, can only replicate inside host cells
What are host cells?
include all groups of cellular organisms
What are virons?
viruses outside the host cell, inert infectious particles
each type of virus is essentially a piece of ___ enclosed in a ___, only one type of ___ is found in the iron of a given virus
nucleic acid/capsid/nucleic acid
___ viruses have 3 PRO, ___ viruses have >100 PRO
Hosts supply the ___ for viruses, as well as the ___ and ___ to reproduce
What are the parts that make up a viron?
- envelope: lipid containing layer with embedded PRO
- capsid: PRO coat around n.a.
- nucleic acid
- capsomeres: PRO subunit that makes up to capsid
What does the nucleocapsid refer to?
the capris and the nucleic acid
PRO in the envelope are ___ and encoded on the ___
Shape is determined by:
the nature of capsomeres
Describe helical viruses
cylindrical, typical of plant viruses, spiral RNA core attached to identical capsomeres
Describe polyhedral viruses
several possible shapes, most common is the icosehedron (20 triangular faces), some contain more faces by having clusters of polyhedral on the surface (ex. HPV)
complex viruses are composed of ___ parts, the most complex are ___ which are made to infect ___
What are viroids?
closed single strand RNA circles, replication is dependant on host machinery, disease is caused when the viroid overtakes the host
What are some examples of viroid diseases?
cadang cadang, potato spindle tuber)
Where are prions?
only one PRO, cause neurological disease
What are some examples of prion diseases?
mad cow, scrapie, CJD, VCJD, kuru