inflammation Flashcards

(40 cards)

1
Q

5 cardinal signs of inflammation

A

Heat
Redness
Swelling

Pain
Loss of Function

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2
Q

goal of minimizing inflammation

A

minimize collateral damage

stop inflammatory process, down regulate inflammatory signal and get back to normal

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3
Q

why get rid of heat

A

increases cellular activity

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4
Q

why get rid of redness

A

its been theres vasodilation (increase in blood flow)

hyperaemia

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5
Q

why get rid of pain

A

its from pressure of swelling (mechanical) and chemical irrational of nerve

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6
Q

why get rid of swelling

A

swelling means increased osmotic pressure

and hydrostatic pressure in vessel

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7
Q

osmotic pressure is pulling or pushing

A

pulling

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8
Q

osmotic pressure

A

pulling

pressure to prevent flow of water across membrane via osmosis

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9
Q

hydrostatic

A

pushing
pressure on the walls

by systolic force

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10
Q

what mediates vasodilation

A

histamine

serotonin

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11
Q

what mediates increased vascular permeability

A

bradykinin
histamine
serotonin

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12
Q

what mediates chemotaxis

A

histamine
a bunch of kines

mono, kalli, lympho kines

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13
Q

what mediates fever response

A

prostaglandiins

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14
Q

what mediates pain

A

bradykinin
prostaglandins
hageman factor

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15
Q

if theres a vascular response, what changes in the area

A

vasodilation then constriction

slowing blood flood

accumulation of interstitial fluid

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16
Q

if theres a hemostatic response, what changes in the area

A

retraction / sealing off blood vessels

formation of platelet clots

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17
Q

if theres a cellular response, what changes in the area

A

leukocytes move to the area

18
Q

if theres an immune response, what changes in the area

A

activation of complement system

19
Q

purpose of ice

A

strong evidence it helps with pain

decrease metabolism of good cells, decrease secondary cell damage

20
Q

T/F strong evidence ice helps with secondary cell death

21
Q

purpose of rest

A

minimize further injury

22
Q

purpose of compression

A

increase pressure in tissue

counteract hydrostatic pressure

23
Q

purpose of elevation

A

reduce hydrostatic pressure in vessel

24
Q

whats Peace and Love

A

Protect elevate avoid inflammations, modalities, compress, education

optimal loading, vascularization, exercise

25
is ice machine better than ice
same
26
goal of managing edema
reduce viscosity | thin out the snot
27
how to manage edema
soft tissue massage electric mm pumping compression
28
how to manage swelling
facilitate resorption of fluid ``` soft tissue massage mm pump elect lympth draining compression ```
29
is normal intra articular pressure positive or negative
slightly negative
30
if injured, intraarticular pressure becomes
more positive
31
fluid moves in and out of joint through
``` synovial membrane (with movement) cartilage / bone interface ```
32
How to reduce intra articular pressure
joint movement | change joint pression (traction, compression)
33
Outcome measures to know if you're doing good
VAS circumferential measures LEFS MDC MCID
34
whats MDC
minimal detectable change
35
whats MCID
minimal clinically important difference
36
VAS MCID
13mm for initial less than 34 28mm for initial score more than 67
37
what circumferential measure if MDC
>0.5 cm
38
MDC in edema swelling volume
150ml
39
LEFS MDC MCID
9 | 9
40
DASH MDC MCID
8-17 | 10.2