Inflammation / Healing Process - 1 Flashcards Preview

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Flashcards in Inflammation / Healing Process - 1 Deck (49)
0

large injury that results in failure of musculoskeletal structures

macrotrauma

1

overuse, cyclic loading, friction injuries. small stresses that cause injury over time

microtrauma

2

primary injury can cause swelling and ultrastructural changes like damaging the blank of the ankle

ligaments

3

two causes of secondary injury

enzymatic injury, metabolic injury

4

example of an enzymatic secondary injury

lysosomal mechanism (eating good tissue)

5

example of metabolic injury

inadequate waste removal

6

inflammation is a coordinated chemical response with blank

vascularity

7

heat and redness are caused by increased blank

vascularity

8

swelling is caused by blockage of blank drainage

lymphatic

9

pain is caused by a physical blank or blank irritation

pressure, chemical

10

loss of function is caused by blank

pain/swelling

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activate blank receptors with joint mobes to inhibit blank receptors

mechano, pain

12

blood clotting aka

hemostasis

13

protective --> controlled motion --> return to function

aka inflammation, proliferation, maturation

14

vasoconstriction in injured vessels is the blank response to injury

vascular

15

protein rich fluid escapes into surrounding tissue which pulls blank with it due to being blank

water, hydrophilic

16

pressure exerted by a column of water

hydrostatic pressure

17

pressure resulting from attraction of fluid by free proteins

osmotic pressure

18

basophils, eosinophils, neutrophils are all pretty important in blank

inflammation

19

release antibodies into bloodstream

b lymphocytes

20

cell deprived of oxygen

hypoxia

21

when hypoxia occurs in cells after injury, blank metabolism kicks in, so the blank pump slows down which increases cellular blank

anaerobic, sodium potassium, acidosis

22

removal of noxious stimuli, growth of capillary beds, collagen forms, easily injured tissue

proliferation phase

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fibroblasts produce blank

collagen

24

fibroblast growth occurring in connective tissue

fibroplasia

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composed of capillaries, fibroblasts, and myofibroblasts

granulation tissue

26

initially type blank collagen is formed

3

27

wound contraction that pulls epithelial layer inwards

myofibroblasts

28

wound closure takes about blank days in muscle/skin

5-8

29

wound closure takes blank days in tendon and ligament

3-6 weeks

30

wound contraction begins about blank days after injury

5

31

growth of new blood vessels during proliferation

angiogenesis

32

longest phase in healing process and can last more than a year

maturation

33

goal of maturation pt

return to normal funciton

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collagen provides extracellular blank

framework

35

synthesis of scar dominates over lysis will result in blank or blank scars

hypertrophic, keloid

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a red scar means more blank is occurring

healing

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restarting acute phase without getting out of it

recurrent inflammation

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healing where scar tissue restores normal function

acceptable

39

healing where injury is more likely

minimal

40

healing where no tissue is really repaired

failed

41

collagen goes from type 3 to type 1 during this healing phase

maturation

42

tendon healing is only blank to blank

minimal, acceptable

43

inflammation occurs in blank tissue

vascularized

44

capillary filtration pressure formula

(CHP + TOP) - (THP + COP)

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CHP is

capillary hydrostatic pressure

46

top is

tissue osmotic pressure

47

thp is

tissue hydrostatic pressure

48

cop is

capillary osmotic pressure