Inflammatory/ neoplasia Bone dz Flashcards Preview

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Flashcards in Inflammatory/ neoplasia Bone dz Deck (23):
1

Osteitis

Inflammation of bone
-general term

2

Periostitis

Inflammation of periosteum

3

Osteomyelitis

Inflammation of medullary cavity
-most common inflammatory condition

4

Bone sequestrum

-Fragment of dead bone
-surrounded by inflammatory cells and exudate

(chronicity --> involucrum)

5

Involucrum

Sequestrum surrounded by DENSE RING of reactive bone

6

Infectious Osteomyelitis

-most common in neonatal farm animals
-hematogenous distribution

-Fungi are more common in domestic animals

7

Viral osteomyelitis
-Viruses w/ true inflammation

-Hog cholera
-Canine hepatits virus

--> endothelial damage --> metaphyseal hemorrhage

8

Viral osteomyelitis
-Virus w/o true infection

-Distemper virus
-Osteoclast infection --> growth retardation lattice (disrupt growth plate modeling)

-FeLV
-infection/necrosis of hematopoietic cells --> myelosclerosis

9

Metaphyseal Osteopathy

Osteomyelitis of trabecular bone w/ periosteal bone formation
- Multiple swollen joints & fever
- Young, Lg breed dogs

Oblasts die & matrix reduces --> trabeculae collapse --> (Bilateral) parallel fracture at growth plate

10

Rads of Metaphyseal osteopathy

Alternatig dense and lucent areas parallel to physis
(BILATERAL)

11

Aseptic necrosis of bone

-Retain growth plate
-lack mineralization

12

Legg Calve Perthes Dz

Asceptic necrosis of femoral head --> collapse of articular cartilage
--Miniature dogs

13

Clincal signs of Bone neoplasias

-lameness
-pain
-hypercalcemia
-increase ALP
-fractures

14

Tumors w/ abundant fibrous stroma -->

NEW bone formation

Tumors w/ little stroma (lymphoma) --> no bone/lysis

15

Hypertrophic osteopathy

Progressive, bilateral periosteal bone formation of diaphysis of distal limbs

Always have some kind of space occupying mass

16

Osteochondromas

***NOT a neoplasm**
Multiple masses adj to physes of long bones & ribs
*possible malignant transformation

-Cat --more common in adults and in flat bones

17

Fibrous dysplasia

Multifocal lytic intraosseous lesions
-young animals

-Pre-existing bone exchanged for well-diff fibrous tissue & woven bone
**no Oblast

18

Bony cysts

Sequelae of:
-osteochondrosis
-degenerative joint dz
-ischemia
-malformation

19

Name 6 Primary neoplasms of bone

1. Ossifying fibromas
2. Chondromas
3. Chondrosarcomas
4. Osteomas
5. Osteosarcomas
6. Multilobular tumor of bone

20

Ossifying fibroma

-Benign
-maxilla/mandible
-Young HORSE & CATTLE

Fibrous tissue (fibroblasts) w/ woven bone and osteoblasts

21

Chondroma/sarcoma

Tumors of hyaline cartilage
-NO osteoid
**Mets to LUNGS
**Bypass LN

22

Osteoma/sarcoma

Central = in medullary cavity
Perio-steal = from periosteum onto medullary
Paro-steal = from periosteum into soft tissue

* Rads = common to see starburst

23

MultiLobular Tumor of Bone

-Single Nodular Immobile mass
- partially mineralized
- separated by CT
-Flat bones (skull, hard palate)
-DOGS