Inheritance, Variation and Evolution Flashcards

1
Q

What is asexual reproduction? What does this produce? Why? - IVE

A

Asexual production is the production of offspring with 1 parent. Produces an IDENTICAL CLONE as genetic material doesn’t mix

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2
Q

What process of cell division does asexual reproduction use? - IVE

A

Mitosis -
Chromosomes in a nucleus are copied, chromosomes and chromatids are moved towards poles. Chromosomes separate and cell divides into 2 identical daughter cells

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3
Q

What are cells that are produced by mitosis used for? - IVE

A

Growth of tissues
Repair of damaged tissues
Replacement of worn out cells

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4
Q

What is asexual reproduction?

A

Reproduction to produce offspring involving the fusion of gametes to form a zygote

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5
Q

What percentage of a zygote’s chromosomes does each gamete contain? - IVE

A

50%

When they combine they form a full set of chromosomes

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6
Q

What type of cell division creates GAMETES ONLY? - IVE

A

Meiosis

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7
Q

Describe the process of meiosis cell division. How many cells does meiosis produce? - IVE

A

In each cell there are 4 chromosomes, which duplicate to form 8 individual chromosomes, with the pairs lining up, genetic information swapping between chromosomes and the cell dividing twice. Produces 4 CELLS

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8
Q

Name 2 advantages and disadvantages each of sexual reproduction - IVE

A

+ve: creates variation in offspring, disease less likely to affect all people, species can adapt to new environments
-ve: time and energy needed to find a mate, not possible for isolated individuals

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9
Q

Name 2 advantages and disadvantages each of asexual reproduction - IVE

A

+ve: Population can increase rapidly, only 1 parent needed, faster than sexual reproduction, time and energy efficient
-ve: doesn’t lead to variation in a population, disease may affect all individuals, may only be suited to 1 habitat

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10
Q

What is DNA? What is a chromosome? - IVE

A

DNA is in double helix shape, carrying genetics, determines characteristics
Chromosomes are long threads or DNA made up of genes

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11
Q

What are genes? What do they do? - IVE

A

A small section of DNA. Each gene codes a sequence of amino acids to make a protein. This is what is passed on to offspring

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12
Q

What is the (entire human) genome? What does this enable us to do? - IVE

A

The complete set of DNA found in an organism (all humans)

Enables us to search for genes linked to different diseases, understand inherited diseases and treatment

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13
Q

Describe the structure of DNA (mention backbone, links between) - IVE

A

Constructed of a double helix backbone, supported by links between a pair of nucleotides (A-T OR C-G) made from sugar and phosphate sections

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14
Q

What are base pairs and what are the 4 specific base pairs? - IVE

A

Base pairs are chemical cross links between the 2 strands of DNA
(Adenine, Thymine), (Cytosine, Guanine)

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15
Q

How do ribosomes know which specific proteins to synthesise? - IVE

A

A copy of the DNA code for the protein is released from the nucleus, called mRNA, which enters the ribosome and synthesises a specific protein based on the code.

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16
Q

What are mutations? Can they be inherited? - IVE

A

A change in a gene or chromosome. A rare, random change in genetic material
Can be inherited

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17
Q

What can cause mutations? - IVE

A

Spontaneous mutations
Ionising radiation
Chemical mutagens (tar in cigarette smoke)

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18
Q

What are 1. substitution and 2. insertion mutations? - IVE

A
  1. A specific base is substituted with another base, meaning a different amino acid is synthesised
  2. An extra base is inserted between bases, and a different protein is synthesised
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19
Q

What are 1. deletion and 2. inversion mutations? - IVE

A
  1. A base is removed between bases and results in a different protein being synthesised
  2. A base changes order, resulting in a different amino acid, and maybe protein, being made
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20
Q

How many nucleotides makes up a specific reading for 1 amino acid? - IVE

A

A specific amino acid is made of 3 nucleotides, as they are read this way when entering a ribosome. This is called a triplet code

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21
Q

What is fertilisation? Explain this in terms of human chromosomes - IVE

A

The fusion of the nuclei of male and female gametes, in humans each with 23 chromosomes to provide the total number of 46 for a human body

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22
Q

What are gametes? What are the human gametes? - IVE

A

Sex cells. The human sex cells are sperm and eggs (ovums)

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23
Q

What are alleles? Name an example - IVE

A

Different versions of the same gene, for example eye colours (blue allele, brown allele)

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24
Q

What are a genotype and a phenotype? - IVE

A

Genotype are the alleles that an organism has for a particular characteristic. These alleles are expressed as the phenotype, the visible characteristics of an organism as a result of genes

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25
What are dominant and recessive alleles? (Are they expressed, how are they represented) - IVE
Dominant - always expressed even if 1 allele is present, represented by a capital letter Recessive - only expresses if 2 of these alleles are present. Represented by a lower case letter
26
What are homozygous and heterozygous alleles? - IVE
Homozygous - alleles are identical for each characteristic (AA/aa) Heterozygous - alleles are different for each characteristic (Aa)
27
How do you construct punnett squares? - IVE
Discover the parental genotypes. Split them into single alleles (DOM in CAPS, recess in lower) and add around edges of Punnett square. Combine in each box and calculate probabilities of each outcome
28
What determines the biological sex of a human? - IVE
Males have XY chromosomes (heterozygous), females have XX chromosomes (homozygous)
29
What are the effects of cystic fibrosis? Is it caused by a faulty dominant or recessive allele? What does this mean? - IVE
Cystic fibrosis is a disorder which clogs the lungs with thick mucus which damages them Caused by recessive allele, meaning that only homozygous recessive alleles display the trait
30
What are the effects of polydactyly? Is it caused by a faulty dominant or recessive allele? What does this mean? - IVE
Polydactyly is a condition causing someone to have extra fingers or toes. Caused by a dominant allele, meaning if you have the dominant allele, you expressed this trait
31
Describe the steps of gene therapy - IVE
A faulty gene is identified, enzymes used to cut out normal allele from donor. These alleles are copied and inserted into the cells of a person with a mutation or faulty gene
32
What problems are there with gene therapy? - IVE
Alleles may not be inserted into every target cell, may not be inserted into the right place in chromosomes
33
What is pedigree analysis? - IVE
Pedigree analysis is the use of data on family history of genetic disorders to predict whether family members will inherit a disease
34
What did Mendel discover? How did he do this? - IVE
Mendel discovered that if you breed red flowered pea plants with white, all offspring had red flowers. Of the offspring that were bred, some had red flowers, some had white
35
How can we apply our modern understanding to Mendel's discoveries? (In terms of Alleles) - IVE
We now know that one gene (RED) was dominant, whilst white was recessive
36
Why was Mendel's work not accepted by most scientists at the time? - IVE
When he presented his work he didn’t fully understand it, his work was not published widely, couldn’t explain the science behind it
37
What is variation? - IVE
Variation is the process by which members of a species are not identical
38
What is genetic variation? Give human examples - IVE
Variation due to the combination of 23 chromosomes from each parent in fertilisation Blood group, skin colour, eye colour, sex
39
What is environmental variation? Give examples in humans - IVE
Characteristics that can be affected by diet, lifestyle, culture, accidents Scars, language and accent, weight
40
How can mutations lead to a rapid change in a species? - IVE
If a mutation is displayed in the phenotype and it is of benefit to the organism in a specific environment, then it can lead to the advancement of a species when passed on
41
What is Natural Selection? - IVE
A process where organisms that are better suited to an environment will survive and have more offspring and pass these traits on to offspring (Survival of the Fittest)
42
Which scientist discovered the idea of natural selection, an example of which is the peppered moth - IVE
Charles Darwin came up with the Theory of Evolution. In 19th century, pollution made bark on trees become darker. Light coloured moths weren’t camouflaged and were eaten. Dark moths were and passed this trait onto offspring
43
What is selective breeding? What examples are there of this? (animal and plant)- IVE
Where humans breed plants/animals to produce desired characteristics Breeding Cows that produce lots of milk Breeding disease resistant wheat plants
44
What are the benefits and risks of selective breeding? - IVE
+ves: new varieties can produce high yields of a product, animals can be bred that don’t cause harm (cows without horns) -ves: reduced genetic variation can lead to attack by diseases, can create physical problems unknowingly
45
What is genetic modification? - IVE
A process which artificially transfers genetic information from one donor cell to another organism(s)
46
What are the steps of genetic modification? - IVE
Identification of the desired trait, of which the gene responsible for this is cut out of the chromosome with an enzyme. The gene is transferred into a plasmid from a bacterial cell, and then into a bacterial cell where it can rapidly reproduce
47
What is currently done to improve crop yields/human life using genetic modification? - IVE
Produce human insulin for type 1 diabetics Make herbicide resistant crops that can tolerate the herbicide Make 'golden rice' which helps improve human vitamin A production
48
What risks and benefits are there of genetic modification? - IVE
+ve: faster and more efficient than selective breeding, improves crop yields or quality, makes herbicide resistance -ve: transfer of genes may cause widespread harm, not ethical to interfere with nature, can cause allergic reactions
49
How can plants be cloned by cuttings? - IVE
A branch from a parent plant is cut off with lower leaves removed and the stem placed in compost. Plant hormones used to develop. After a few weeks a clone plant grows
50
How can plants be cloned through tissue culture? How is this better/worse than taking cuttings? - IVE
Small pieces of plants are grown in vitro using agar jelly with hormones and nutrients. More expensive than taking cuttings but can preserve rare species or grow on a large scale
51
How are embryo transplants performed in animals? Do they produce unique or identical offspring? - IVE
Sperm from a bull from high dairy yield herd artificially inseminates a cow. Zygotes develop into embryos and are harvested. These embryos are split into smaller embryos and transplanted into host mothers. IDENTICAL.
52
How is adult cell cloning performed? Does this produce unique or identical offspring? - IVE
An unfertilised egg cell (without nucleus) is combined with the nucleus of a body cell to have full set of chromosomes. Given an electric shock to stimulate cell division. When the embryo is a ball of cells it is implanted into womb. Identical to body cell sheep
53
How does evolution by natural selection work? - IVE
As an environment changes, individuals with certain traits are more suited to it and more likely to survive to pass these traits onto offspring. This leads to gradual evolution, as those without useful traits die out
54
What was Lamarck's theory of evolution? What supposed example is there of this? Was this theory correct? - IVE
A characteristic that is used more by an organism becomes enhanced and one that isn’t disappears. Any improved features are passed to offspring. An example is a giraffe's long neck, used to reach tall trees. This idea was WRONG
55
What was Darwin's proposed theory of evolution? - IVE
Individual organisms have traits more suited to an environment which means they are more likely to breed successfully. These traits are passed onto offspring, meaning a species gradually evolves
56
What problems were there with Darwin’s proposed theory of evolution? - IVE
The theory challenged religious ideas that God made all animals and plants (creationism), insufficient evidence for Darwin's case, not proven for 50 years after publication
57
What is Alfred Wallace known for contributing towards the idea of evolution? - IVE
The idea of speciation, the formation of new and distinct species in evolution
58
What are fossils? What can they be made in? - IVE
The preserved remains of a dead organism from millions of years ago. Preserved in amber, peat bogs, tar, ice, rock
59
How do fossils support Darwin's theory of evolution? - IVE
Fossils show the most basic, old organisms and more developed organisms, which show the evolution of species
60
Why are there gaps in the fossil record? - IVE
Many soft-bodied forms of life have been destroyed be geological activity like volcanic eruptions or earthquakes
61
What is antibacterial resistance? How is this an example of evolution? - IVE
Random mutations occur in the genes of bacterial cells, which protect the cell from antibiotics. Bacteria without the mutation die from antibiotics, but the resistant strain can reproduce and evolve
62
What is a specific example of antibiotic resistant bacteria? How can antibiotic resistance be prevented? - IVE
MRSA Doctors should not inappropriately prescribe antibiotics where they aren’t needed, patients should always complete a full course of antibiotics to ensure all bacteria are killed
63
What is extinction, and what can cause it to occur? - IVE
Extinction is when an entire species is wiped out | Caused by new diseases, new predators, new competitors, changes to an environment or a catastrophic geological event
64
What is the Linnaean system of classification? What mnemonic helps remember this? - IVE
Kingdom, Phylum, Class, Order, Family, Genus, Species | KIDS PREFER CANDY OVER FRESH GREEN SALAD
65
What is the binomial system of naming species? Why is this important to scientists? - IVE
Genus + Species | Allows scientists to classify species accurately and individually
66
What is Carl Woese's 3 domain system? (Name the 3 domains and their components) - IVE
Archaea - primitive bacteria usually living in extreme environments Bacteria - true bacteria Eukaryota - protists, fungi, plants and animals