Flashcards in Insulin Therapy Deck (21):
What are the 2 insulin secretion responses?
What is the rate of basal insulin secretion?
What are the biphasic insulin secretion responses?
Preformed readily releasable (5-10 mins)
Mobilization phase (1-2 hours)
Where is insulin secreted in to?
Give an example of rapid acting analogue and its duration.
Give an example of short acting insulin and duration.
Humulin S (soluble)
Give an example of an intermediate acting insulin and duration.
Humulin I (isophane)
Give an example of long acting analogue insulin and duration.
Give an example of Rapid acting analogue/intermediate mix.
Give an example of a short acting/intermediate mix.
Describe the basal bolus regime and why is it used?
1 basal (pre bed)
3 prandial (pre meal)
Mimics normal insulin secretion
What is the target blood glucose a) pre meal b) 1-2hrs after meal?
Why should T1DM patients use analogue insulin?
When is the peak action of a) analogue b) soluble insulin?
a) 60-90 mins
b) 2-4 hrs
How is dosage of insulin calculated?
50% is basal
50% is prandial (over 3 injections)
What is a) DAFNE and b) TIM?
a) dose adjustment for normal eating
b) tayside insulin management
What factors can affect insulin absorption?
When may you need IV insulin?
Hyperosmolar Hyperglycaemic state
What prevents lipohypertrophy?
rotate injection sites
What can affect dosage given?