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Flashcards in Insulin Therapy Deck (21):
1

What are the 2 insulin secretion responses?

Prandial
Basal

2

What is the rate of basal insulin secretion?

0.25-1.5 units/hour

3

What are the biphasic insulin secretion responses?

Preformed readily releasable (5-10 mins)
Mobilization phase (1-2 hours)

4

Where is insulin secreted in to?

Portal vein

5

Give an example of rapid acting analogue and its duration.

Humalog/ Novorapid
0-5hrs

6

Give an example of short acting insulin and duration.

Humulin S (soluble)
0-8hrs

7

Give an example of an intermediate acting insulin and duration.

Humulin I (isophane)
0-20hrs

8

Give an example of long acting analogue insulin and duration.

Lantus/Levemir
0-24hr

9

Give an example of Rapid acting analogue/intermediate mix.

Humalog 25/Novomix30

10

Give an example of a short acting/intermediate mix.

Humulin M3

11

Describe the basal bolus regime and why is it used?

4 injections
1 basal (pre bed)
3 prandial (pre meal)
Mimics normal insulin secretion

12

What is the target blood glucose a) pre meal b) 1-2hrs after meal?

a)3.9-7.2
b) <10

13

Why should T1DM patients use analogue insulin?

avoid hypos

14

When is the peak action of a) analogue b) soluble insulin?

a) 60-90 mins
b) 2-4 hrs

15

How is dosage of insulin calculated?

0.3 u/kg
50% is basal
50% is prandial (over 3 injections)

16

What is a) DAFNE and b) TIM?

a) dose adjustment for normal eating
b) tayside insulin management

17

What factors can affect insulin absorption?

pen accuracy
leakage
lipohyphertrophy
injection depth
exercise

18

When may you need IV insulin?

DKA
Hyperosmolar Hyperglycaemic state
Acute illness
Fasting patients

19

What prevents lipohypertrophy?

rotate injection sites

20

What can affect dosage given?

Sepsis/Acute illness
steroid therapy

21

Should insulin be continued in hypoglycaemia?

YES
Treat hypo AND continue insulin