Integumentary System Flashcards
the process of cells dying in order to form the vital protective barrier that helps enable the animal’s survival
Keratinization
What is another name for the Integumentary System
The Common Integumentary System
List the 7 functions of the Integument
- Prevent desiccation
- Prevent infection
- Thermoregulation - vasoconstriction vs vasodilation
- Excretion - water, salt, organic wastes
- Sensation - touch + pressure > input to CNS
- Vitamin D synthesis
- Storage - nutrients
the outer, non-vascular layer of skin that acts as a waterproof shield
Epidermis
the deep, vascular layer of skin that makes up the majority of skin
Dermis
the 3rd layer of the integument that acts as a thermoinsulator and a mechanical shock absorber
Hypodermis (Subcutaneous Layer)
separates the two layers of the integument
Epithelial Basement Membrane
What are the 4 components of the common integument?
- Epidermis
- Dermis
- Hypodermis
- Epithelial Basement Membrane
cells in the epidermis that produce a tough, fibrous, waterproof protein that gives skin its resiliency and strength
Keratinocytes
What are the majority of cells found in the epidermis?
Keratinocytes
long-reaching cells in the epidermis that produce pigment to be used by keratinocytes
Melanocytes
a dark pigment stored in membrane bound granules that is used to protect keratinocytes from UV rays
Melanin
membrane-bound granules that store melanin
Melanosomes
epidermal-specific macrophages that phagocytize microinvaders and stimulate other aspects of the immune system
Langerhans Cells
half-dome cells found at epidermal-dermal junctions that aid in the sensation of touch
Merkel Cells
the combination of a Merkel cell and a sensory nerve ending
Merkel Disc
What 3 types of cells are commonly affected in skin cancer?
- Squamous Cells
- Melanocytes
- Basal Cells
List 3 common skin cancers seen in vet med
- Malignant Melanoma
- Squamous Cell Carcinoma
- Basal Cell Tumors
a deadly form of skin cancer that results from abnormal changes in the genetic programming of melanocytes
Malignant Melanoma
What species is commonly affected by Malignant Melanoma? What 3 locations do the nodules appear?
- Aged grey horses
- Under tail base, in perianal areas, in the scrotum
a malignant form of skin cancer that is aggressively invasive locally, particularly to local lymph nodes
Squamous Cell Carcinoma
What visible symptom does squamous cell carcinoma produce?
circular, ulcerated lesions
Squamous cell carcinoma is common in what 5 species?
- Dogs
- Cattle
- Horses
- Cats
- Merino ewes
slow-growing tumors that stem from the basement layer of the epidermis, in hair follicles, and in sebaceous glands that do not spread but are recurrent
Basal Cell Tumor