Intervertebral Disc

Question 1

What type of collagen make up the intervertebral disc?

Answer 1

Annulus fibrosus- Type I

Nucleus pulposus- Type II

Question 2

What nerve innervates the annulus fibrosus?

Answer 2

Sinuvertebral nerve

Question 3

What changes occur in the intervertebral disc with aging?

Answer 3

Increase:
lactate
enzyme activity
keratan/chondroitin ratio

Decrease:
   nutrition transport
   water content
   pH
   proteoglycans

There is no change in collagen content

Question 4

What changes occur in the intervertebral disc with aging?

Answer 4

Increase:
   lactate
   enzyme activity
   keratan/chondroitin ratio
   conversion to fibrocartilage

Decrease:
   nutrition transport
   water content
   pH
   proteoglycans

There is no change in collagen content

Question 5

What is the most common location for annular tears or fissures in the intervertebral disc?

Answer 5

posterolateral