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Flashcards in Intestinal pathology practical Deck (13):
1

Pathophysiology of IBD/lymphoplasmacytic enteropathy

SI mucosa infiltration --> progressive villous atrophy, maladsorption and PLE --> progressive weight loss and ascites secondary to hypoalbuminaemia

2

Gross and microscopic appearance - MAP/Johne's. Stain?

-Prominent intestinal mucosal folds
-macrophages (mostly) and lymphocytes)
-shown using ZN stain as MAP is acid fast within macrophage cytoplasm

3

Define leiomyoma. Malignant? Location? Spp? prognosis?

Tumour of smooth muscle cell origin
Benign - leiomyosarcomas are malignanat
-Can occur anywhere in stomach (obstructive if near pylorus)
-dogs mainly
-good prognosis, often an incidental finding in older dogs

4

Intussusception - causes - 4

Anything causing increased peristalsis (parvovirus, parasite or bacterial infection). Also intestinal FB.

5

Lesions of grass sickness/equine dysautonomia - 4

-Caecal impaction (autonomic nerves have degenerated so much reduced motility)
-linear ulceration of lower oesophagus
-gastric distension (with/out rupture along the greater curvature)
-dilated SI with watery ingesta

6

Other species that can get grass sickness - 2. Other names?

Hares
Cats (Key-Gaskell syndrome/Feline dysautonomia/Feline Autonomic Polygangioneuropathy)

7

What type of virus is FIP?

coronavirus

8

2 main types of FIP?

wet effusive or dry non-effusive

9

Tissues affected in FIP? 5

-serosa
-pleura
-meninges
-retinas
-pericardium

10

Location of autonomic nerve plexi in the intestines - 2

in the submuscosa and also between the two muscle layers (i.e. the muscularis externa)

11

Cyathostomes - another name

small strongyles

12

Why do cyathostomes cause disease in horses?

Synchronous emergence from intestinal walls results in a PLE. Often concurrent clinical biochemistry reveals low plasma protein levels and enzyme evidence of muscle breakdown.

13

Appearance - cyathostomes in intestines

Numerous dark nodules over the mucosal surface