Intro to Membranes + Bacterial Cell Structure Flashcards

1
Q

What kind of movement is common in the phospholipid bilayer and why

A

Lateral movement, provides fluidity and flexibility. Flip-flop movement is rare because polar head is not stable in hydrophobic core

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2
Q

In high temperatures, there is _____ (more/less) room between phospholipids and the membrane permeability _______ (increases/decreases)

A

more, increases

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3
Q

In low temperatures, there is _____ (more/less) room between phospholipids and the membrane permeability _______ (increases/decreases)

A

less, decreases

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4
Q

How do membranes adapt to high & low temperatures

A

High: increase hydrocarbon tail length (increase hydrophobicity), decrease C=C bonds (they cause kinks, increase cholesterol content (stiffens/thickens membrane, increases hydrophobicity)
Low: Increase C=C bonds (“kick” apart), decrease tail length, increase cholesterol (acts as a spacer)

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5
Q

Non-polar amino acids are

A

hydrophobic

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6
Q

List substances from most permeable to least permeable

A

hydrophobic (np) molecules (O2, CO2, N2) -> small uncharged polar molecules (H2O, Glycerol, Ethanol) -> large uncharged polar molecules (glucose, sucrose) -> ions (Na+, K+, H+, Cl-)

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7
Q

How does passive transport work

A

Molecules flow from an area of high concentration to low concentration (water follows solute). Water undergoes passive transport by osmosis.

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8
Q

What is a risk when water rushes into the cell in animal cells

A

cells can burst (osmotic lysis)

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9
Q

What is a risk when water rushes out of the cell in animal cells

A

cells can shrink

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10
Q

Does facilitated diffusion require energy

A

no

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11
Q

Name the two forms of facilitated diffusion

A

Channel “tunnel” protein and carrier “revolving door” protein

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12
Q

Is facilitated diffusion specific

A

yes

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13
Q

Why perform active transport?

A

expel waste, concentrate nutrients in cell

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14
Q

Describe the sodium potassium pump

A

Sodium
Out
Potassium
In

Positive
Out
Negative
In
3Na+ out 2K+ in
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15
Q

Define coupled transport, give an example

A

Energy released by one gradient is used to establish another gradient.
Sodium/Potassium pump is used to pull glucose up its gradient into the cell.

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16
Q

Explain exocytosis

A

Bulk transport out of the cell, proteins from golgi transported in vesicle that fuses with plasma membrane to secrete proteins

17
Q

Explain Endocytosis/Phagocytosis

A

Bulk transport into the cell, non specific, vesicle forms from plasma membrane, transports to lysosome (digestive organelle)

18
Q

Explain Receptor mediated endocytosis

A

Endocytosis of a specific ligand (anything that binds a receptor) placed in vesicle, receptors recycled, ligand goes to lysosome to be digested/recycled.

19
Q

Bacteria HAVE:

A

fimbriae, cell membrane, cell wall, cytoplasm, flagella, ribosomes, DNA in nucleoid region

20
Q

Bacteria DO NOT have:

A

Membrane bound organelles (eg. Golgi, ER, chloroplasts)

21
Q

What is the motile structure of Bacteria, explain it

A

Bacteria flagellum: rotates like a corkscrew to allow movement, powered by H+ gradient
Basal apparatus anchors filaments into cell wall/membrane

22
Q

What is peptidoglycan

A

structural polysaccharide

23
Q

What is lipoteichoic acids role

A

link cell wall to membrane

24
Q

Explain the differences between Gram negative and Gram positive bacterial cell walls

A

Positive: thick layer of peptidoglycan
Negative: thin layer of peptidoglycan, but has an outer membrane (but not a major permeability layer)

25
What are Fimbriae and Biofilm
Forms of attachment in prokaryotes
26
How does the antibiotic penicillin work
Disrupts transpeptidation step (works well on Gram positive bc more PG)
27
How does colonization begin at birth
"Good" skin bacteria in birth canal so that baby is bathed in it before bad bacteria can reach it, around 600 species of bacteria in breast milk
28
What is humans only source of vitamin K
E Coli
29
Bacteria can aid in....
development of gut, digesting complex carbs, train immune system to distinguish harmful & helpful