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Flashcards in Intro to Pharm Deck (13)
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1

4 ways to name drugs

Chemical name
Generic name
Proprietary (Trade) name
Street name

2

Pharmacodynamics

What the drugs do to the body
Studies the effects of drugs on body processes

3

Pharmacokinetics

What the body does to drugs
Studies the movement of drugs in the body

4

2 factors important for receptor binding

Affinity
Shape/specificity

5

Agonists

Have receptor affinity and intrinsic activity
Bind and cause a response
Often exogenous derivatives of an endogenous agonist

6

Antagonists

Have receptor affinity but lack intrinsic activity
Bind, cause no action

7

2 ways naloxone works

Blocks binding of agonist
Displaces agonist since it has a higher affinity for the receptor

8

ED50

Dose required to produce a therapeutic effect in 50% of the population

9

TI is calculated by dividing...

Toxic dose 50/effective dose 50

10

3 things to consider when determining which route of administration to use

1. Drug characteristics
2. Patient characteristics
3. Therapeutic objectives

11

Enteral administration

Through the GI tract
Gives systemic effects
Includes oral, sublingual and rectal

12

Parenteral administration

Does not involve the GI tract
Usually injections

13

5 routes of drug administration

Enteral
Parenteral
Inhalational
Topical
Transdermal