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Flashcards in Intro to Microbio Deck (15)
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1

3 determinants of disease

Host
Pathogen
Environment

2

5 factors in determining whether a host is susceptible to an infection

Immunity
Host defenses
Concomitant diseases
Exposure
Medications

3

4 factors in determining whether a pathogen has the ability to cause human disease

Virulence factors
Reservoirs
Transmissibility
Robustness

4

Chain of infection

Susceptible host
Pathogen
Reservoir
Portal of Exit
Mode of transmission
Portal of entry

5

6 major ways pathogens are transmitted to humans

Direct contact
Indirect contact (fomite)
Droplet
Airborne
Vehicle (single contaminated source spreads infection to multiple hosts)
Vector borne

6

5 ways pathogens enter the human body

Mucosal surfaces
Skin
Inhalation
Ingestion
Nosocomial via medical devices

7

5 major classes of organisms that cause disease in humans

Bacteria
Viruses
Fungi
Parasites
Prions

8

2 most clinically relevant ways of classifying bacteria

Phenotype (morphology, gram stain)
Growth requirements (aerobes, anaerobes)

9

Gram reaction colours

Purple = gram +
Pink = gram -

10

5 targets of antibiotic action

Folate metabolism
Nucleic acid synthesis
Protein synthesis
Cell membrane
Cell wall synthesis

11

3 most common Gram + aerobic cocci

Staph
Strep
Enterococcus

12

2 most common Gram - rods (aerobic/facultative anaerobe)

Enterobacteriaceae
Pseudomonas

13

Fungi can be split into... (2)

Yeast
Mould

14

2 most common yeast

Candida (oval shaped)
Cryptococcus (big circles in CSF)

15

Most common mould

Aspergillus