Ischaemia

Question 1

Definition

Answer 1

Interrupted blood flow to the myocardium which leads to interrupted supply of 02 and nutrients

Question 2

Different types of hypoxia

Answer 2

• hypoxic: poor 02 inspiration levels or poor Pa02
• anaemic: poor transportation of 02
• cytotoxic: good inspiration of 02, poor ability to absorb at tissue level
• stagnant; abnormal delivery of 02 e.g. occlusion of vessel

Question 3

Aetiology of ischaemia

Answer 3

Poor blood flow:

• thrombosis
• embolism
• cardiac failure
• trauma

Question 4

Issues relating to supply

Answer 4

• inspired 02
• pulmonary function
• blood constituents
• blood flow
• endothelium lining disruption
• tissue mechanism

Question 5

Issues relating to demand

Answer 5

• increased exercise

- increased stress levels

Question 6

Consequences of ischaemia

Answer 6

-reduced 02 supply
-increased anaerobic respiration
-cell death
affects tissues differently depending on structure:
-dysfunction
-pain
-physical damage