L1: Overview Flashcards

1
Q

The time period when animals were first domesticated

A

8000 BC - 1000 BC

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2
Q

The time period when plants were first cultivated

A

5000 BC

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3
Q

Argued that active humors in the body served as bearers of hereditary traits

A

On the Seed of the Hippocratic treatise

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4
Q

Proposed that the male semen contained a vital heat capable of producing offspring of the same form as the parent

A

Aristotle

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5
Q

Studied reproduction and proposed the theory of epigenesis

A

William Harvey

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6
Q

A theory stating that an organism develops from the fertilized egg by a succession of developmental events that eventually transform the egg into an adult

A

Theory of Epigenesis

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7
Q

A theory stating that the fertilized egg contains a complete miniature adult called a homonculus

A

Theory of Preformation

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8
Q

Proposed the cell theory which states that all organisms are composed of cells derived form preexisting cells

A

Matthias Schleiden
Theodor Schwann

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9
Q

Disproved the idea of spontaneous generation

A

Louis Pasteur

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10
Q

Formulated the theory of natural selection

A

Charles Darwin

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11
Q

Formulated and proposed independently natural selection which is based on the observation that populations tend to contain more offspring than the environment can support

A

Alfred Wallace

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12
Q

Published a paper in 1866 showing how traits were passed from generation to generation in pea plants and how traits are inherited

A

Gregor Mendel

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13
Q

Independently formulated the chromosome theory of inheritance

A

Walter Sutton
Theodor Boveri

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14
Q

A theory stating that inherited traits are controlled by genes residing on chromosomes faithfully transmitted through gametes, maintaining genetic continuity from generation to generation

A

Chromosome Theory of Inheritance

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15
Q

Published experiments showing DNA was the carrier of genetic information in bacteria

A

Oswald Avery
Colin Macleod
Maclyn McCarty

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16
Q

Described the structure of DNA and were awarded a Nobel Prize in 1962

A

James Watson
Francis Crick

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17
Q

Used to cut any organism’s DNA at specific nucleotide sequences, producing a reproducible set of fragments

A

Restriction Enzymes

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18
Q

The use of recombinant DNA technology and other molecular techniques to make products

A

Biotechnology

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19
Q

The transfer of heritable traits across species using recombinant DNA technology creates […]

A

transgenic organisms

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20
Q

When was Dolly the sheep cloned via nuclear transfer?

A

1996

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21
Q

When did the Human Genome Project begin?

22
Q

Branch of biology that deals with heredity and variation

23
Q

Classically defined as a unit of heredity

24
Q

A segment of DNA with information to produce a functional product

25
The 4 important macromolecules
- Nucleic Acids - Proteins - Carbohydrates - Lipids
26
The largest macromolecule found in living cells
DNA
27
The building blocks of DNA
Nucleotides
28
The characteristics of a cell depend on the types of [...] it makes
proteins
29
The entire collection of proteins that a cell makes at a given time
Proteome
30
4 functions of proteins
- shape and structure - transport of ions and molecules - biological motors - cell-cell recognition and signaling
31
[...] accelerate chemical reactions and are a particularly important category of proteins
Enzymes
32
The 4 nitrogenous bases of DNA
- Adenine - Thymine - Guanine - Cytosine
33
A three-base sequence which specifies one amino acid among 20 possible choices
Codon
34
The process of using a gene sequence to affect the characteristics of cells and organisms
Gene Expression
35
**Gene Expression** *Step 1*: The DNA sequence within a gene is copied into a nucleotide sequence of RNA
Transcription
36
**Gene Expression** *Step 2*: The sequence of nucleotides in an mRNA provides the information to produce the amino acid sequence of a polypeptide
Translation
37
**Gene Expression** *Step 3*: A polypeptide [...]
folds into a three-dimensional structure
38
**Gene Expression** *Step 4*: The functioning of proteins largely determines [...]
cell structure and fuction
39
Any characteristics than an organism display
Traits
40
4 levels of biological organization in observations and theories
- Molecular - Cellular - Organism - Population
41
Differences in inherited traits among individuals within a population
Genetic Variation
42
Heritable changes in the genetic material that may alter the expression or function of a protein that a gene specifies
Gene Mutations
43
Refers to the effects of environmental variation on an individual's traits
Norm of Reaction
44
A human genetic disease that prevents individuals from breaking down phenylalanine in foods
Phenylketonuria
45
Two copies of a chromosome are called [...] of each other
homologs
46
**Field of Genetics** Examines the relationship between the transmission of genes from parent to offspring and the outcome of the offspring's traits
Transmission Genetics
47
**Field of Genetics** Studies how the genetic material works at the molecules level
Molecular Genetics
48
**Field of Genetics** Explains the prevalence of certain alleles within populations of individuals
Population Genetics
49
2 reasons why model organisms are used for experiments
1. Genetic mechanisms were the same in most organisms 2. The model organisms had characteristics that made them especially suitable for genetic research
50
The 7 model organisms discussed
- *Escherichia coli* - *Saccharomyces cerevisiae* - *Caenorhabditis elegans* - *Drosophila melanogaster* - *Danio rerio* - *Mus musculus* - *Arabidopsis thaliana*