He studied Streptococcus pneumoniae and found that R-type transformed into S-type
Frederick Griffith
The process observed by Griffith wherein R-type became S-type
Transformation
The unidentified substance causing transformation
Transforming Principle
They (3) realized that Griffith’s observations could be used as part of an experimental strategy to identify the genetic material
- Oswald Avery
- Colin Macleod
- Maclyn McCarty
A second set of experimental results indicating that DNA is the genetic material came from […] and […]
- Alfred Hershey
- Martha Chase
[…] and […] are used to label phage proteins and DNA respectively
- 35S
- 32P
He discovered DNA in 1869
Friedrich Miescher
The 2 purine bases
- Adenine
- Guanine
The 3 pyrimidine bases
- Thymine
- Cytosine
- Uracil
He proposed that regions of proteins can fold into a particular type of secondary structure
Linus Pauling
He pioneered many of the biochemical techniques for the isolation, purification, and measurement of nucleic acids from living cells
Erwin Chargaff
What is Chargaff’s Rule?
A + G = T + C
