L26 - Nervous Layer Flashcards

(38 cards)

1
Q

What are the three layers of the eyeball?

A

Fibrous layer (sclera, cornea), vascular layer (iris, ciliary body, choroid), nervous layer (pigment layer, neural layer/retina).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the Latin word for retina and what does it mean?

A

Rete; it means “net”.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Where does the retina extend from and to?

A

From the optic disc to the ora serrata.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the surface area of the retina?

A

About 1,094 mm².

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Where is the retina thickest and thinnest?

A

Thickest near the optic disc (560 µm), thinnest at the foveal floor (100 µm), thinner towards the periphery (180 µm at equator, 100 µm at ora serrata).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How far is the fovea from the optic disc edge?

A

11.8° or 3.4 mm temporal to the optic disc edge.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the size of the optic nerve head?

A

1.86 × 1.75 mm.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the cross diameter of the macula?

A

3 mm of intense pigmentation, surrounded by a 1-mm-wide zone of less pigmentation.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How much retinal distance does one degree of visual angle correspond to?

A

288 μm on the retina.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How does fundus color vary by pigmentation?

A

Lightly pigmented individuals have a blonde fundus (sub-retinal elements visible); darkly pigmented individuals have a more pigmented fundus (sub-retinal elements not seen).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the main visible landmarks of the retina?

A

Retinal blood vessels, peripheral retina and ora serrata, optic disc, area centralis (macula) with fovea and foveola.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What arteries supply the retina?

A

Central retinal artery and posterior ciliary artery.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What veins drain the retina?

A

Arcade veins → central retinal vein; choroidal veins → vortex veins.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the three retinal zones?

A

Zone 1 (near periphery), Zone 2 (mid periphery), Zone 3 (far periphery).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the ora serrata?

A

Transition zone between retina and pars plana; underlying the vitreous base; associated with increased risk of retinal detachment.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the width and location of the ora serrata?

A

Width: 2.1 mm temporally, 0.7 mm nasally; 6 mm nasally and 7 mm temporally from the limbus; 25 mm nasally from the optic disc.

17
Q

What is the optic disc?

A

Circular or slightly oval area (about 1.5 mm), contains a depression known as the physiological cup.

18
Q

What are the dimensions of the optic disc?

A

Vertical diameter: 1.86 mm; horizontal diameter: 1.75 mm; 3.4 mm from the macula.

19
Q

What is the normal cup-to-disc ratio (CDR)?

20
Q

What is the ISNT rule?

A

Neuroretinal rim thickness order: Inferior > Superior > Nasal > Temporal.

21
Q

What is the area centralis (macula)?

A

Located at the posterior pole, temporal to disc, elliptical, 5.5 mm diameter, corresponds to 15° of visual field.

22
Q

What are the subdivisions of the area centralis?

A

Umbo (0.15 mm), FAZ (0.5 mm), fovea (1.5 mm), parafoveal area (2.5 mm), perifoveal area (5.5 mm), foveola (0.35 mm).

23
Q

What is the macula lutea?

A

Oval yellow zone, 3 mm diameter, yellow color due to xanthophyll, histologically more than 1 layer of ganglion cells (6-8 layers).

24
Q

What is the fovea?

A

Centre of area centralis, 4 mm temporal to disc, 0.8 mm below horizontal meridian, 1.85 mm diameter, 0.25 mm thick, corresponds to 5° of visual field.

25
What is the foveal avascular zone (FAZ)?
Capillary-free zone in the centre of the fovea, diameter 0.20–0.6 mm, important landmark in fluorescein angiography.
26
What is the foveola?
0.35 mm diameter, 0.13 mm thick, represents 1.25° of visual field, highest visual acuity, thinnest part of retina, only cones and Müller cells, devoid of ganglion cells.
27
What is the umbo?
Tiny depression in the centre of the foveola, corresponds to foveal reflex, intensely bright spot of light due to reflection from foveal depression.
28
What is the potential space between sensory retina and RPE called?
Subretinal space.
29
What is the retinal pigment epithelium (RPE)?
Single layer of hexagonal cells with melanin and lipofuscin, joined by tight junctions (outer blood-retinal barrier).
30
What are the functions of the RPE?
Absorption of scattered light, blood-retinal barrier, visual pigment regeneration, synthesis of growth factors, maintenance of retinal adhesion, phagocytosis, electrical homeostasis, repair and regeneration.
31
What are age-related changes in RPE melanin?
Pigments fuse with lysosome and break down, absorb stray light, serve as free radical stabilizer, bind toxins and retinotoxic drugs.
32
What are age-related changes in RPE lipofuscin?
Accumulates with age, derived from ingested outer segment lipids and digested membrane fragments damaged by light or oxidation.
33
What are the three main neurons of the retina?
Neuron I (perception elements), Neuron II (conductive and associative elements), Neuron III (conductive elements).
34
What information do photoreceptors carry?
Intensity and temporal information.
35
What information is not carried by individual photoreceptors?
Type of sense and spatial origin of the signal.
36
What is the length of cones at the periphery and at the fovea?
40 μm at periphery (shortest), 80 μm at fovea (longest).
37
What is the structure of a cone?
Conical outer segment with iodopsin pigment in lamellar discs (1000–1200 discs/cone), inner segment, cilium, nucleus, cone foot/pedicel.
38
What are the three types of cone pigments?
Erythrolabe (long wavelength/red), chlorolabe (medium/green), cyanolabe (short/blue).