L5 - Skeletal System Flashcards

(65 cards)

1
Q

What are the classes of bones?

A

Flat bones, irregular bones, long bones, short bones.

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2
Q

What is the process of bone formation called?

A

Ossification.

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3
Q

What does the skeletal system consist of?

A

Bones (skeleton), joints, cartilages, ligaments.

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4
Q

What type of tissue is bone/osseous tissue?

A

Supporting connective tissue.

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5
Q

What are the main components of bone matrix?

A

Extracellular protein fibres and ground substance.

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6
Q

What fraction of bone weight is calcium phosphate?

A

About 2/3.

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7
Q

What fraction of bone weight is collagen fibres?

A

About 1/3.

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8
Q

What percentage of bone mass is made up of osteocytes and other cells?

A

2%.

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9
Q

What are the five main functions of bones?

A

Support, protection, storage of minerals and fats, blood cell production, movement.

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10
Q

How do bones provide support?

A

They offer structural support for the whole body, framework for attachment of organs and soft tissues, and attachment sites for muscles.

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11
Q

How do bones function in storage?

A

They store minerals (calcium, phosphorus) and fats (yellow bone marrow stores adipose tissue).

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12
Q

Where is most of the body’s calcium stored?

A

In bones as calcium salts.

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13
Q

How is calcium deposition and removal from bones controlled?

A

By hormones, to maintain homeostasis.

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14
Q

Where does blood cell production (haematopoiesis) occur?

A

In red bone marrow.

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15
Q

What types of blood cells are produced in bone marrow?

A

Red blood cells (erythrocytes), white blood cells, platelets.

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16
Q

How do bones facilitate movement?

A

They provide surfaces for muscle, ligament, and tendon attachment and act as levers when stimulated.

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17
Q

How many bones are in the adult skeleton?

A

206.

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18
Q

What are the two main subdivisions of the skeleton?

A

Axial skeleton and appendicular skeleton.

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19
Q

What does the axial skeleton include?

A

Facial and cranial bones, vertebrae, ribs, sternum (80 bones).

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20
Q

What does the appendicular skeleton include?

A

Upper and lower limbs, anchored to the axial skeleton (126 bones).

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21
Q

What are the two main types of bone tissue?

A

Compact bone and spongy bone.

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22
Q

What are the characteristics of compact bone?

A

Dense, smooth, and homogeneous.

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23
Q

What are the characteristics of spongy bone?

A

Meshwork of uneven spaces.

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24
Q

What are the four groups of bones based on shape?

A

Flat bones, irregular bones, long bones, short bones.

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25
What are examples of flat bones?
Ribs, sternum, bones of the skull.
26
What are examples of irregular bones?
Vertebrae, facial bones.
27
What are examples of long bones?
Femur (leg), humerus (arm).
28
What are examples of short bones?
Carpals (wrist), tarsals (ankle).
29
What is the structure of a long bone?
Central shaft (diaphysis) surrounding marrow/medullary cavity, made of compact bone, surrounded by periosteum, expanded ends (epiphyses) covered by articular cartilage.
30
What does the periosteum do?
Covers outside of bones, provides a route for nerves and blood vessels, isolates bone from surrounding tissues, important for bone growth and repair.
31
What attaches skeletal muscle to bone?
Tendons.
32
What attaches bone to bone?
Ligaments.
33
What is the endosteum?
A membrane that covers spongy bone of marrow cavity and inner surfaces, active during bone repair, remodelling, and growth.
34
What are the three main types of cells in bone?
Osteoblasts, osteocytes, osteoclasts.
35
What is the function of osteoblasts?
Produce new bone matrix (ossification), promote deposition of calcium salts in the organic matrix.
36
What happens when an osteoblast is surrounded by calcified matrix?
It differentiates into an osteocyte.
37
What is the function of osteocytes?
Maintain bone matrix, repair and recycle calcium salts in bony matrix.
38
What is the function of osteoclasts?
Break down bone matrix (osteolysis/resorption), secrete enzymes and acids to release stored minerals, regulate phosphate and calcium concentration in body fluids.
39
What is a closed/simple fracture?
An internal fracture seen only on x-rays.
40
What is an open/compound fracture?
A fracture that projects through the skin, more dangerous due to infection/bleeding risk.
41
What is a communicated fracture?
Several breaks result in many small pieces between two large segments.
42
What is an impacted fracture?
One fragment is driven into the other, usually as a result of compression.
43
What is a transverse fracture?
Breakage of bone shaft along its long axis.
44
What is an oblique fracture?
Breakage occurs at an angle that isn’t 90 degrees.
45
What is a displaced fracture?
Produces new abnormal bone arrangement.
46
What is a non-displaced fracture?
Retains the normal alignment of bones.
47
What is a compression fracture?
Occurs in vertebrae when subjected to extreme stress, often associated with osteoporosis.
48
What is a spiral fracture?
Produced by twisting stresses that spread the length of the bone.
49
What is the first step in fracture repair?
Formation of a fracture hematoma (6-8 hours after injury).
50
What is a fracture hematoma?
A large blood clot that forms after a fracture, stopping bleeding and forming a fibrous meshwork.
51
What happens after a fracture hematoma forms?
Lack of blood flow leads to osteocyte death and area of dead bone along bone shaft.
52
What is the second step in fracture repair?
Callus formation (48 hours after injury).
53
What forms the internal callus?
A network of spongy bone that unites inner edges of fracture.
54
What forms the external callus?
Cartilage and bone that encircle and stabilize outer edges of fracture.
55
What is the third step in fracture repair?
Spongy bone formation-osteoblasts replace central cartilage with spongy bone, uniting broken ends.
56
What is the fourth step in fracture repair?
Compact bone formation and remodelling.
57
Name nutrients important for bone tissue.
Vitamin D, calcium, vitamin K, fluoride, magnesium, omega 3 fatty acids.
58
What is the role of vitamin D in bone tissue?
Needed for calcium absorption.
59
What is the role of calcium in bone tissue?
Required to make calcium phosphate and calcium carbonate, which form hydroxyapatite crystals for bone hardness.
60
What is the role of vitamin K in bone tissue?
Supports bone mineralization, has a synergistic effect with vitamin D.
61
What is the role of fluoride and magnesium in bone tissue?
Structural components of bone tissue.
62
What is the role of omega 3 fatty acids in bone tissue?
Reduces inflammation, which may interfere with function of osteoblasts.
63
What is calcium required for in the body?
Bone mineralisation, heart rate regulation & contraction, health of teeth, coagulation of blood, nerve impulse conduction, contraction of skeletal and smooth muscles.
64
What is hypocalcemia?
Low levels of calcium.
65
What is hypercalcemia?
High levels of calcium.