L3 - Active membrane transport Flashcards
(12 cards)
Active membrane transport
Movement against chemical or electrochemical gradient
Requires energy
Via primary or secondary active transporters
Primary active transport (Na+ pump)
- Each cycle: 3Na+ out, 2 K+ in against conc gradient
- Uses up significant amount of ATP
- Establishes membrane gradients
Secondary active transport
- Uses established Na+ gradient to pump other solutes against their gradients
- Movement of Na+ down conc gradient provides energy
Antiporter
Na+ comes into cell
Other solute goes out
Symporter
Na+ and other solute both go into cell
Types of active transport
- Primary (Na+ pump)
- Secondary (symporter, antiporter)
Vesicular transport
Exocytosis
Endocytosis
Transcytosis
Exocytosis
Vesicle forms in cell, comes in close contact with membrane, substance gets released
Requires ATP
e.g. release of hormones
Endocytosis
Membrane creates vesicle by surrounding subtance, brings it into cell
- Receptor mediated
- Phagocytosis
- Bulk-phase
Requires ATP
Receptor mediated
surface of emmbrane is activated to form pits
Phagocytosis
membrane extends out and gathers substances
larger than receptor-mediated
Bulk-phase
solutes settle onto membrane, depression formed, vesicle formed.