Flashcards in L7_Bacterial Structure and Function 2 Deck (11):
Describe the Flagellum of prokaryotes
A stiff corkscrew like structure that is rotated by a molecular motor embedded through the wall and driven by a proton gradient across the membrane.
What do the following drugs do to bacteria? Aminoglycosides, Tertracyclines, Macrolides
Aminoglycosides - Attack small subunit, interfere with initiation
Tertracyclines- Attack small subunit, transfer of t-RNA+aa sets to ribosome
Macrolides- Attack rRNA of large subunit
What is the rate limiting step in binary fission?
What size are bacterial ribosomes?
Describe the make up of a spore, name two bacteria that can form them.
Very rugged, dehydrated package containing the bacterial genome with a minimal entourage of macromolecule. The spore can survive all normal cleaning and sets the standard for autoclaving. when nutrients and water returns the spore can unpack back into vegetative cells. Bacillus and Clostridium
What are the growth phases bacteria undergo when in a culture vessel of limited size?
Lag, Log, stationary, death
What determines a bacterias tolerance to oxygen?
The ability to breakdown and detoxify oxygen radicals using superoxide dimutase, catalase, and cytochrome C.
What is a bacteria that encode for both fermentation and respiration pathways? give and example
Facultative anaerobe (E. Coli)
What is bacteria that can withstand oxygen radicals but lacks an ETC?
What is a bacteria that requires ETC as its source of energy? Give an example
Obligate Aerobe (M. Tuberculosis)