Lab Tests Flashcards

(81 cards)

0
Q

What is the difference between a Comprehensive Medical Panel and a Basic Metabolic Panel?

A

The comprehensive medical panel has all the tests as the basic metabolic panel plus Albumin, Total Protein, and the liver tests of liver function

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1
Q

What eight values does a Basic Metabolic Panel test?

A

Glucose, Sodium, Potassium, Chloride, Carbon Dioxide, Calcium, Creatinine, and BUN

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2
Q

What are the tests for liver function?

A

ALP, ALT, AST, and Bilirubin

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3
Q

Volume of packed RBCs in 100 mL of blood

A

Hematocrit

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4
Q

In what diseases is hematocrit lowered?

A

Acute blood loss, anemia, cancers, cirrhosis, malnutrition, vitamin B and C deficiencies, leukemia, and renal failure

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5
Q

In what conditions is hematocrit increased?

A

Dehydration, hypovolemia, and polycythemia vera

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6
Q

Which drug can cause a low hematocrit?

A

Penicillin

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7
Q

What is the critical value of hematocrit?

A

<15%

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8
Q

What can a critically low hematocrit lead to?

A

Heart Failure

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9
Q

A protein substance in RBCs that is composed of an iron and globin?

A

Hemoglobin

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10
Q

What conditions can lead to decreased hemoglobin levels?

A

Anemia, cancers, kidney disease, and excess IV fluid

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11
Q

What conditions cause increased hemoglobin levels?

A

Dehydration, polycythemia, high altitudes, and COPD

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12
Q

Low hemoglobin levels put the patient at risk for what complications?

A

Angina, heart attack, and heart failure

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13
Q

Too high hemoglobin levels can lead to what complications?

A

Stroke and organ infaction

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14
Q

What are the critical values of hemoglobin?

A

20

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15
Q

What are signs and symptoms of anemia?

A

Fatigue, pallor, and tachycardia

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16
Q

What is the appropriate BUN range?

A

10-20 mg/dL

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17
Q

What is a BUN level a measure of?

A

Liver function, and indirectly, kidney function

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18
Q

What conditions result in abnormally low BUN levels?

A

Liver failure, over hydration, negative nitrogen balance, nephrotic syndrome and a low protein diet

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19
Q

What causes a negative nitrogen balance?

A

Malnutrition and malabsorption

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20
Q

What is the medical term for increased BUN levels?

A

Azotemia

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21
Q

What are the prerenal causes of azotemia?

A

Reduced blood volume, reduced renal blood flow, GI bleeding, excessive protein feeding, excess protein catabolism, and sepsis

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22
Q

What conditions might cause reduced blood flow to the kidneys?

A

CHF and MI

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23
Q

What are the renal causes of azotemia?

A

Renal disease, renal failure, and nephrotoxic drugs

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24
What are the postrenal causes of azotemia?
Urethral obstruction and bladder obstruction
25
What is creatinine a byproduct of?
Muscle catabolism
26
What are the normal ranges of Creatinine in males and females?
0.6-1.2 in males, 0.5-1.1 in females
27
What do high creatinine levels indicate?
Acute and chronic renal failure, reduced renal blood flow, cancers, lupus, and rhabdomyolysis
28
What do decreased creatinine levels indicate?
Muscle atrophy and reduced muscle mass
29
What can cause a transient elevation in creatinine levels?
Diets high in meat
30
What is bilirubin made from?
The heme of old or damaged RBCs
31
At what serum level of bililrubin would the patient be jaundice?
2.5 mg/dL
32
What would cause a rise in indirect bilirubin levels?
Hemolysis and hepatocellular injury
33
What would cause a rise in direct bilirubin levels?
Obstruction and cancers
34
What would cause a rise in total bilirubin levels?
Biliary obstruction
35
What is the critical level of bilirubin in adults?
>12 mg/dL
36
What is the critical level of bilirubin in newborns?
>15 mg/dL
37
Newborn jaundice is generally caused by what type of bilirubin?
Indirect
38
How can the nurse prevent increased bilirubin levels?
Avoid hemolysis of blood products and lab specimen and protect samples from bright lights
39
What does an alkaline phosphate test monitor?
Diseases of the liver and bone
40
What would cause an increase in alkaline phosphates?
Biliary obstruction and cholestatic hepatitis
41
What does a serum aspartate aminotransferase test (AST) monitor?
Enzymes found in the heart and liver muscle
42
What does a serum alanine aminotransferase test (ALT) monitor?
Enzymes found in the liver
43
Of the liver enzyme function tests, which is the most specific measurement of the liver enzymes for hepatocellular disease?
Alanine Aminotransferase
44
When a hepatocellular injury occurs, what happens to the levels of Aspartate Aminotransferase and Alaninie Aminotransferase?
They rise
45
What tests are done to measure coagulation time?
PT, aPTT, PTT, INR
46
What is the normal Prothrombin Time?
11-12.5 seconds
47
What conditions does a decrease in prothrombin time indicate?
Thrombophlebitis and pulmonary embolus
48
What does an increased prothrombin time indicate?
Anticoagulation therapy, liver disease, coagulation defect, and malasorption
49
Which anticoagulation drugs cause a change in Prothrombin time?
Aspirin and Coumadin
50
What is the normal INR range?
0.7-1.8
51
What is a therapeutic INR range?
2.0-3.5
52
Why is INR and PT used?
To provide a better interpretation of the results
53
What can increase coagulation times and counteract coagulation therapy?
Vitamin K
54
What should the nurse assess on a patient with prolonged prothrombin times?
Bleeding tendencies like hematuria, bruising, petechiae, and back pain
55
What is the normal aPTT range?
21-40 seconds
56
What is the critical value of an aPTT?
70 seconds
57
When is an aPTT used?
When the patient is on heparin
58
What is the normal PTT range?
60-70 seconds
59
What is a critical PTT value?
100 seconds
60
What does PTT evaluate?
Intrinsic system of clotting
61
What does a PT evaluate?
Extrinsic clotting system
62
What would cause a decrease in an aPTT/PTT?
Ovarian, pancreatic, and colon cancer
63
What would cause an increase in an aPTT/PTT?
Cirrhosis, vitamin K deficiency, anticoagulants
64
When should the aPTT be completed?
30-60 minutes before the next scheduled heparin dose
65
How would a nurse assess a patient on anticoagulants for bleeding?
Look at the urine, skin, gums, and stool
66
How can heparin be reversed?
Protamine sulfate
67
What is the total protein value a combination of?
Prealbumin, albumin, and globulins
68
Protein test indicating nutritional status and liver function
Preablumin
69
Why is prealbumin a good indicator of nutritional status?
Because it has a short half-life
70
In which patients is a prealbumin level especially important in?
Those receiving TPN
71
Proteins formed in the liver that maintain colloidal osmotic pressure
Albumin
72
What does albumin transport?
Drugs, hormones, and enzymes
73
Building blocks of antibodies, glycoproteins, lipid proteins, and clotting factors
Globulins
74
What are the most common critical values called in to the nurse?
Potassium, Glucose, WBCs, Hemoglobin, Hematocrit, Platelets, Calcium, and Troponin
75
What is a normal fasting glucose range?
70-100 mg/dL
76
What is a normal WBC count?
5000-10000/mcL
77
What is a normal platelet count?
150,000-400,000/mcL
78
What is the normal range of Hemoglobin in males and females?
14-18 g/dL in males and 12-16 g/dL in females
79
What is the normal Hematocrit range in males and females?
42%-52% in males and 37%-47% in females
80
What does a hematocrit level of <24% indicate?
The need for a transfusion