Labs Flashcards by Adam Gardner

anti-centromere

CREST

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anti-desmoglein

pemphigus vulgaris (desmosomes)

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anti-glomerular BM

Goodpastures

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anti-IgG

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anti-mitochondrial (AMA)

primary biliary cirrhosis (female, PHTN, cholestasis)

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anti-neutrophil (ANCA)

MPO-ANCA/p-ANCA - microscopic polyangiitis, Churg Strause

PR3-ANCA/c-ANCA - Wegener (granulomatosis with polyangiitis)

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anti-platelet

idiopathic thrombocytopenic purpura

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ANA

SLE

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anti-topoisomerase

diffuse systemic scleroderma

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anti-transglutaminase, anti-gliadin, anti-endomysial

Celiac’s

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apple core lesion

colorectal cancer (left-sided)

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azurophilic peroxidase + granular inclusions on granulocytes and myeloblasts

Auer rods (promyelocytic AML)

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bacitracin sensitivity

sensitive Group A Strep

resistant Group B Strep

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basophilic nuclear remnants on RBCs

Howell-Jolly bodies (no spleen)

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basophilic stippling of RBCs

lead poisoning or sideroblastic anemia

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bronchogenic apical lung tumor on imaging

Pancoast tumor (can compress sympathetic ganglion and cause Horner syndrome)

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brown tumor of bone

hyperparathyroidism or osteitis fibrosa cystica (hemosiderin gives pigment)

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cardiomegaly with apical atrophy

Chagas (Trypanosoma cruzi)

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cellular crescents in glomeruli

rapidly progressing crescentic glomerulonephritis

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dark tumor cells surrounding pale neurofibrils

Homer-Wright rosettes (neuroblastoma, medulloblastoma, retinoblastoma)

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pseudomonas colonies in lungs

Cystic fibrosis

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depigmentation of neurons in substantia nigra

parkinsons

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desquamated epithelial cells in sputum

Curshmann spirals (asthma, can result in whorled mucous plugs)

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disarrayed granulosa cells in eosinophilic fluid

Call-Exner bodies (granulosa cell tumor of ovary)

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enlarged cells with intranuclear inclusion bodies

owl eye cells of CMV

enlarged thyroid cells with ground glass appearance

little orphan annie eyes (papillary carcinoma of thyroid)

eosinophilic cytoplasmic inclusion in hepatocyte

Mallory body (alc liver disease)

eosinophilic inclusion in nerve cell

Lewy body (parkinsons)

eosinophilic globule in liver

councilman body (toxic or viral hepatitis, YF)

eosinophilic inclusion in hippocampal or cerebellar nerve cells

Negri bodies of rabies

giant B cells, bilobed nuclei, prominent inclusions

owl eyes, Reed-Sternberg cells of Hodgkins lymphoma

glomerulus like body surrounding vessel in germ cells

Schiller Duval body (yolk sac tumor)

crew cut on X-ray

B-thalassemia, SCD (marrow expansion)

hCG elevated

pregnancy, hyditiform mole, choriocarcinoma

granulomatous heart nodules

aschoff bodies (rheumatic fever)

heterophile antibodies

infectious mono (EBV)

hexagonal, double pointed, needle like crystals in bronchial secretions

bronchial asthma (Charcot-Leyden crystals)

D-dimers

DVT, PE, DIC

hilar lymphadenopathy, peripheral granulomatous lesion in middle or lower lung

ghon complex, primary TB

honey comb lung

Interstitial pulmonary fibrosis

hypercoagulability (migrating DVTs, vasculitis)

Trousseua syndrome (adenocarcinoma of pancreas or lung)

hypersegmented neutrophils

megaloblastic anemia (B12 will have neuro symptoms, folate will not)

hypertension, hypokalemia, metabolic alkalosis

Conn syndrome (primary aldosteronism)

hypochromic, microcytic anemia

lead poising iron deficiency thalassemia

increased AFP in amniotic fluid

dating error anencephaly neural tube defect

increased uric acid levels

gout lesch nyhan syndrome tumor lysis syndrome loop and thiazide diuretics

iron containing nodules in alveolar septum

furruginous bodies (asbestosis, increased chance of mesothelioma)

keratin pearls on skin biopsy

squamous cell carcinoma

large lysosomal vesicles in phagocytes, immunodeficiency

Chediak Hegashi (congenital failure of phagolysosome formation)

lead pipe appearance of colon on barium enema x-ray

ulcerative colitis from loss of haustra

linear IgG in glomerular BM

Goodpasture

low serum ceruloplasmin

Wilson

lumpy bumpy appearance of glomeruli

post-strep GN (IgG and C3b)

lytic bone lesions on x-ray

multiple myeloma

mammary gland, blue domed cyst

fibrocystic change of breast

monoclonal antibody spike (M spike)

- MM - MGUS - Waldenstrom macroglobulinemia - primary amyloidosis

mucin filled cell with peripheral nucleus

signet ring (gastrocarcinoma)

narrowing of bowel lumen on barium x-ray

crohns

necrotizing vasculitis of lungs and necrotizing glomerulonephritis

granulomatosis with polyangiitis (wegeners, c/PR3-ANCA) | goodpastures (anti-BM antibodies)

nodular hyaline deposits in glomeruli

Kimmelstein Wilson nodules (diabetic nephropathy)

nutmeg liver

chronic passive congestion on liver due to right heart failure

onion skin periosteal reaction

Ewing sarcoma

optochin response

sensitive: strep pneumo resistent: viridens strep

periosteum raised from bone making triangle

Codman's triangle (osteosarcoma, Ewings, pyogenic osteomyelitis)

podocyte effusion or effacement

minimal change disease

protein aggregates from hyperphosphorylation of tau protein

Alzheimers | Picks

psammoma bodies

meningioma papillary thyroid carcinoma mesothelioma papillary serous carcinoma of the endometrium and ovary

RBC casts in urine

acute glomerulonephritis

rectangular inclusions in Leydig cells

Reinke crystals (leydig cell tumor)

renal epithelial casts in urine

viral/toxic renal injury

rib notching

coarctation of the aorta

sheets of medium sized lymphoid cells with scattered pale, tangible body laden macrophages (starry sky histology)

burkitt lymphoma (8:14, c-myc, associated with EBV

silver staining spherical aggregation of tau protein in neurons

Pick bodies, pick's disease

soap bubble in femur on x-ray

giant cell tumor of bone

spikes on GBM, dome-like sub epithelial deposits

membranous glomerulonephritis

stacks of RBCs

Rouleaux formation (high ESR, multiple myeloma)

stippled vaginal epithelial cells

clue cells (Gardnerella vaginalis)

tennis rackets in langerhans cells

Birbeck granules of langerhans cell histiocytosis

thrombi made of white-red layers

lines of zahn (arterial thrombus, layers of platelets/RBCs)

thumb sign

H. influenza epiglottitis

thyroid like appearance of kidney

chronic bacterial pyelonephritis

tram-track appearance of capillary loops GBM

membranoproliferative GN

triglyceride accumulation in liver cell vacuoles

fatty liver disease (alcoholic or metabolic syndrome)

waxy casts with very low urine flow

chronic end stage renal disease

WBC casts in urine

acute pyelonephritis

WBCs that looked smudged

CLL (almost always B cell)

wire loop glomerular capillary appearance on light microscopy

lupus nephropathy

yellowish CSF

xanthochromia (due to subarachnoid hemorrhage)

Labs Flashcards

(88 cards)