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Pathophys quiz 2 > Labs and shit > Flashcards

Flashcards in Labs and shit Deck (39)
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1

Purpose of labs

establish diagnosis, rule out clinical problem, monitor therapy, establish prognosis, screen for disease, determine effective drug dosage / prevent toxicity

2

Arterial blood collection is used for what?

blood gases (ABG)

3

what 3 tests are used the most?

Basic metabolic panel (7), complete metabolic panel (14), and CBC

4

indications for CBC

routine work up, RBC related symptoms, WBC related symptoms, Platelet related symptoms

5

WBC increase from what type of infection?

bacterial

6

Leukocytosis (increased WBC)

infection, leukemia

7

Leukopenia (decreased WBC)

bone marrow failure, drugs, overwhelming infection, immunosuppressant

8

frequency of wbc

Neutrophils, lymphocytes, monocytes, eosinophils, basophils

9

PMN

phagocytes, 1st to respond to inflammation or infection
2 types, mature=segs, immature=bands.
increased during bacterial infection

10

pancytopenia

all CBC are decreased

11

Lymphocytes

B and T cells, involved in immune reactions, increase in viral infections, decreased is normal in 22% of population

12

Monocytes

active in disposing of foreign and waste material, esp. inflammation

13

eosinophils

respond to allergic run and parasitic infestations.
increased from allergy or parasites

14

basophils (mast cells)

respond to allergic and inflammatory rxn
increase is rare

15

most important RBCs

Hemoglobin and hematocrit

16

RBC

-count of circulating RBCs
-increases in heart or lung disease, dehydration (erythrocytosis-illeness, physiological response/high altitude)
-decreases in kidney disease(anemia (>disease))

17

Hemoglobin

-Measure of total amount of Hg in the blood
-increased- dehydration, polycythemia
-Decreased- macrocyclic anemia (b12, folate def.), normocytic anemia, microcytic anemia (iron def.)

18

Hematocrit

-measure of the % of total blood volume that is made up of RBCs
-increased- Polycythemia
-Decreased- iron deficiency anemia, acute or chronic blood loss

19

MCH

-measure of avg. amount of Hg (wt.) within a RNC
-increased- macrocytosis
-decreased- microcytosis

20

MCV (most important)

-measure of avg. volume of single RBCs
-Increased (macrocytosis)- megaloblastic anemia (b12, folate def.)
-decreased (microcytosis)- iron def. anemia
-normal (normocytosis)
-decrease from chronic disease
-if H&H is low and MCV is low then iron def. anemia is the cause

21

MCHC/RDW

-measure of avg [] or % of Hg within a single RBCs
-decreased= iron def. anemia

22

Platelets

-Bleeding and clotting disorders
-increase- trauma
-decreased- ITP or DIC or drugs

23

ITP

idiopathic thrombocytopenia purpura

24

DIC

disseminated intravascular coagulation (very bad)

25

CMP

BMP + liver tests

26

increased Glucose

polyuria, polydipsia, polyphasic, unexplained weight loss, diabetes mellitus

27

decreased glucose

h/a, visual changes, diaphoresis, confusion, tremor, palpitations, drugs

28

BUN

evaluates kidney function

29

Increased BUN

renal failure (acute or chronic)

30

Creatinine

Evaluate kidney function