Last Day Stuff To Know

Question 1

What causes Hypoalbuminemia?

Answer 1

Low levels of albumin (means you will have more drug in your system)*more common

Cirrhosis
Burns
Acute viral hepatitis
Renal failure and malnutrition

Question 2

What will cause Hyperalbuminemia?

Answer 2

High levels of albumin leading to more drug being bound and less in body

Dehydration
High Protien diets
Neurological diseases

Question 3

What are the acidic (an ionic drugs that bind to albumin?

Answer 3

Phenytoin

Ibuprofen

Naproxen

Warfarin

EX: Asprin will bind to albumin and displace warfarin from it causing an increase in free warfarin

Question 4

What are the basic (cationic drugs) that bind to albumin

Answer 4

Proparanolol

Lidocaine

verapamil

These will displace other drugs off of albumin