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Flashcards in Last Day Stuff To Know Deck (4)
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1

What causes Hypoalbuminemia?

Low levels of albumin (means you will have more drug in your system)*more common

Cirrhosis
Burns
Acute viral hepatitis
Renal failure and malnutrition

2

What will cause Hyperalbuminemia?

High levels of albumin leading to more drug being bound and less in body

Dehydration
High Protien diets
Neurological diseases

3

What are the acidic (an ionic drugs that bind to albumin?

Phenytoin

Ibuprofen

Naproxen

Warfarin

EX: Asprin will bind to albumin and displace warfarin from it causing an increase in free warfarin

4

What are the basic (cationic drugs) that bind to albumin

Proparanolol

Lidocaine

verapamil

These will displace other drugs off of albumin