Flashcards in Lecture 1 - Interactions with Microbes Deck (17)
How have bacteria shaped the world?
Made the world habitable by:
- providing molecular oxygen
- recycling matter
- provide nutrients
- symbiosis with other organisms
Most interactions with bacteria are...
Beneficial to the host
How is transmission of infectious disease different to say, hypertension, for example?
- Can be passed from person to person
- Passed from one to many people (amplification)
What are the general routes of invasion by microbes?
What are the different types of infectious organisms?
What are the features of a generalised bacterium?
- Cell wall made of peptidoglycan
- No nucleus
- Single, circular chromosome
- different ribosomes
Describe the different types of cell wall that bacteria can have
single cell membrane
thick outer layer of peptidoglycan
inner and outer membrane
thin layer of peptidoglycan
Which acids are found in the cell wall of Gram positive bacteria?
Which bacteria are more resistant to drying?
Thicker layer of peptidoglycan
What are the special features found on Gram positive and negative bacteria?
Teichoic acids in the wall
LPS on outer membrane
What is endotoxin
Describe the genomes of viruses
Can be anything!!
RNA or DNA, not both
ds or ss
Circular or linear
What is the generalised structure of viruses?
Protein coat / Capsid
+/- plasma membrane envelope
What are the steps in viral replication?
Transcription of early mRNA
Translation of early proteins
Replication of viral DNA
Transcription of late mRNA
Translation of late proteins
What are the generalised components of the immune system?
1/ Physical barriers
3/ Humoral factors
- from leukocytes or other cells
What are capsules made out of?