Flashcards in Lecture 10: Developmental Genetics II Deck (14):
What is the genetic maternal effect?
Genes transcribed into mRNAs in the ovary during egg formation and translated into proteins after fertilization. Applied to egg polarity genes.
Which egg polarity genes establish the dorsal-ventral axis?
Dorsal, Cactus, Toll
Which egg polarity genes establish the anterior-posterior axis?
Bicoid, Nanos, Hunchback
What is a morphogen?
A protein that varies in concentration and causes different developmental responses as a result of the concentration differences.
Which gene regulates expression of genes responsible for anterior structures and stimulates hunchback?
Which gene regulates expression of genes responsible for posterior structures and inhibits hunchback?
What is the role of Hunchback in gene regulation?
Regulates transcription of genes responsible for anterior structures
What regulates expression of segmentation genes?
Bicoid and Nanos protein gradients
What are the three classes of segmentation genes?
Gap, Pair-rule, Segment-polarity genes
What is the function of Gap genes?
Delete adjacent segments; define broad regions in the egg
What is the function of Pair-rule genes?
Delete same part of pattern in every other segment; define 7 segments of egg
What is the function of Segment-polarity genes?
Affect polarity of segment; defines 14 segments
Homeotic genes affecting development of head and thorax