Lecture 10: Developmental Genetics II Flashcards Preview

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Flashcards in Lecture 10: Developmental Genetics II Deck (14):
1

What is the genetic maternal effect?

Genes transcribed into mRNAs in the ovary during egg formation and translated into proteins after fertilization. Applied to egg polarity genes.

2

Which egg polarity genes establish the dorsal-ventral axis?

Dorsal, Cactus, Toll

3

Which egg polarity genes establish the anterior-posterior axis?

Bicoid, Nanos, Hunchback

4

What is a morphogen?

A protein that varies in concentration and causes different developmental responses as a result of the concentration differences.

5

Which gene regulates expression of genes responsible for anterior structures and stimulates hunchback?

Bicoid

6

Which gene regulates expression of genes responsible for posterior structures and inhibits hunchback?

Nanos

7

What is the role of Hunchback in gene regulation?

Regulates transcription of genes responsible for anterior structures

8

What regulates expression of segmentation genes?

Bicoid and Nanos protein gradients

9

What are the three classes of segmentation genes?

Gap, Pair-rule, Segment-polarity genes

10

What is the function of Gap genes?

Delete adjacent segments; define broad regions in the egg

11

What is the function of Pair-rule genes?

Delete same part of pattern in every other segment; define 7 segments of egg

12

What is the function of Segment-polarity genes?

Affect polarity of segment; defines 14 segments

13

Antennapedia complex

Homeotic genes affecting development of head and thorax

14

Bithorax genes

Homeotic genes affecting development of posterior thorax and abdominal segments