Flashcards in Lecture 34: Development of Pharynx Deck (23):
What is the main organizer for pharyngeal arch development?
What determines craniocaudal segmentation of the pharyngeal arches?
List the aortic arch, cranial nerve, muscle and skeletal derivatives of the 1st pharyngeal arch
Aortic arch: Mandibular
Derivatives: Meckel's cartilage, malleus (articular cartilage), incus (quadrate cartilage)
List the aortic arch, cranial nerve, muscle and skeletal derivatives of the 2nd pharyngeal arch
Aortic arch: Hyoid
Derivatives: Reicher's cartilage, hyoid, stapes, styloid process, muscles of facial expression
What gene influences development of the second pharyngeal arch?
List the cranial nerve and derivatives of the 3rd pharyngeal arch
Derivatives: hyoid, upper pharynx, stylopharyngeus
List the cranial nerve and derivatives of the 4th pharyngeal arch
Derivatives: muscles and cartilages of the larynx and pharynx
List the derivative of the 1st pharyngeal groove
External auditory meatus
List the derivative of the 2nd and 3rd pharyngeal grooves
Cervical sinus (temporary structure)
List the derivatives of the first pharyngeal pouch
Auditory tube, tympanic cavity of middle ear
List the derivatives of the second pharyngeal pouch
Fossa for palatine tonsils
List the derivatives of the third pharyngeal pouch
Inferior parathyroids, thymus
List the derivatives of the fourth pharyngeal pouch
Superior paraythyroids, ultimobranchial body
Which cells secrete calcitonin?
Parafollicular C cells of the thyroid (from ultimobranchial body)
Opening of thyroglossal duct as a small pit at the base of the tongue
What forms Rathke's pouch?
Midline upgrowth from roof of ectodermal stomodeum
List the primordia of the tongue
Lateral lingual swellings (paired), tuberculum impar, copula
Treacher Collins Syndrome
Mutation of TCOF1 gene that disrupts neural crest cells of the 1st pharyngeal arch; facial abnormalities
Cysts: Completely enclosed cavity
Sinus: closed at one end, open at other end to pharynx
Fistula: Tube open at both ends outside pharynx
Subnormal regression of frenulum by mutation in Tbx-22