Lecture 34: Development of Pharynx Flashcards Preview

COB Embryology > Lecture 34: Development of Pharynx > Flashcards

Flashcards in Lecture 34: Development of Pharynx Deck (23):
1

What is the main organizer for pharyngeal arch development?

Foregut endoderm

2

What determines craniocaudal segmentation of the pharyngeal arches?

Hox genes

3

List the aortic arch, cranial nerve, muscle and skeletal derivatives of the 1st pharyngeal arch

Aortic arch: Mandibular
CN: Cranial
Derivatives: Meckel's cartilage, malleus (articular cartilage), incus (quadrate cartilage)

4

List the aortic arch, cranial nerve, muscle and skeletal derivatives of the 2nd pharyngeal arch

Aortic arch: Hyoid
CN: Facial
Derivatives: Reicher's cartilage, hyoid, stapes, styloid process, muscles of facial expression

5

What gene influences development of the second pharyngeal arch?

Hoxa-2

6

List the cranial nerve and derivatives of the 3rd pharyngeal arch

CN: Glossopharyngeal
Derivatives: hyoid, upper pharynx, stylopharyngeus

7

List the cranial nerve and derivatives of the 4th pharyngeal arch

CN: Vagus
Derivatives: muscles and cartilages of the larynx and pharynx

8

List the derivative of the 1st pharyngeal groove

External auditory meatus

9

List the derivative of the 2nd and 3rd pharyngeal grooves

Cervical sinus (temporary structure)

10

List the derivatives of the first pharyngeal pouch

Auditory tube, tympanic cavity of middle ear

11

List the derivatives of the second pharyngeal pouch

Fossa for palatine tonsils

12

List the derivatives of the third pharyngeal pouch

Inferior parathyroids, thymus

13

List the derivatives of the fourth pharyngeal pouch

Superior paraythyroids, ultimobranchial body

14

Which cells secrete calcitonin?

Parafollicular C cells of the thyroid (from ultimobranchial body)

15

Foramen cecum

Opening of thyroglossal duct as a small pit at the base of the tongue

16

What forms Rathke's pouch?

Midline upgrowth from roof of ectodermal stomodeum

17

List the primordia of the tongue

Lateral lingual swellings (paired), tuberculum impar, copula

18

Micrognathia

Small mandible/jaw

19

Agnathia

No jaw

20

Treacher Collins Syndrome

Mutation of TCOF1 gene that disrupts neural crest cells of the 1st pharyngeal arch; facial abnormalities

21

Pharyngeal cysts/sinuses/fistulas

Cysts: Completely enclosed cavity
Sinus: closed at one end, open at other end to pharynx
Fistula: Tube open at both ends outside pharynx

22

Ankyloglossia

Subnormal regression of frenulum by mutation in Tbx-22

23

DiGeorge's Syndrome

Cranial neural crest deficiency; malformation of 1st arch structures/outflow tract; abnormalities in parathyroids, thymus, thyroid, immune systel