Flashcards in Lecture 13- Pathogens 2 Deck (13)
Why are doctors being advised to only prescribe AB when needed?
Antibiotic prescribing leads to development of resistance, due to the incredibly fast evolution of pathogens. This means AB become invalid and don't work, and the patient can no longer be cured. MAJOR WORLD WIDE ISSUE
infectious disease spread from person to person, but they are not at the same place at the same time
-vector bourne (mozzi, healthcare worker)
Person to person
-faecal - oral
decontamination of spills
disposal of sharps/needles
Extra precautions that are done
Gloves for ALL patient contact
Droplet precautions: masks for close contact
Airbourne precautions: respirator mask for staff/patients
viral target cell
eg) HIV and CD4 on helper T-cells
Steps of viral infection
1) Virus attachment and entry
2) nucleic acid released in host
3) + RNA formed
4) Protein synthesus
5) Genome replication
Cause of viral infection symptoms?
symptoms due to damaged cells! Immune system reacts against these.
eg) damaged hepatocytes in Hep C
Rotavirus causes illness by
VP4 spikes o outer shell attach to colonic epithelium >> diarrhea
measure viral antibodies against antigens.
Specific antibodies (for rare illnesses) OR how the numbers of ABs change
change in type of immunoglobulin
genetic determinants that allow a pathogen to cause disease