Lecture 2- Exam 2

Question 1

Released by cells in the small intestines after food ingestion and stimulate insulin secretion when the blood glucose is above the fasting level:

Answer 1

Incretin hormone (GLP1 & GIP)

Question 2

Cells in the small intestins realease GLP1 and GIP after food ingestion and:

Answer 2

stimulate insulin secretion when the blood glucose level is ABOVE the fasting level

Question 3

Absolute deficiency of insulin resulting from autoimmune destruction of pancreatic B cells:

Answer 3

Insulin deficiency (Type 1 DM)

Question 4

Hyperglycemia due to insulin resistance (proceeds overt disease) + progressive loss of insulin secretion:

Answer 4

Type 2 DM

Question 5

Macrovascular complications of DM:

Answer 5

1. brain
2. heart
3. extremities (peripheral vascular disease)

Question 7

List the glycemic goals for a patient with DM:

Answer 7

• Less than 7% A1C
• 80-130 mg/dL blood glucose fasting
• less than 180 mg/dL blood glucose following meal

Question 8

List three ultra-rapid/rapid-acting insulins:

Answer 8

1. insulin lispro (humalog, amelog, lyumjev)
2. insulin aspart (Novolog, fiasp)
3. insulin glulisine (apidra)

Question 9

Category of insulin that is:

RX only
Appearance = clear/colorless
rDNA- human insulin analogs

Answer 9

Ultra-rapid/Rapid-acting insulin

Question 10

Category of insulin that is:

Non-RX
Appearance= clear/colorless
rDNA- human insulin analogs

Answer 10

Short-acting (Regular) insulin

Question 11

List two short-acting/regular insulins:

Answer 11

1. Humulin R
2. Novalin R

Question 12

Category of insulin that is:

NPH- Neutral Protamine Hagedorn
Non-RX
Appearance= cloudy
rDNA- human isophane insulin suspension

Answer 12

Intermediate-acting (NPH) insulin

Question 13

List two intermediate-acting (NPH) insulins:

Answer 13

1. Humulin N
2. Novalin N

Question 14

Cateogry of insulin that is:

RX only
Appearance= clear/colorless
rDNA- human insulin analogs

Answer 14

Long-acting insulin

(same criteria as ultra-rapid/rapid-acting insulin)

Question 15

List three long-acting insulins:

Answer 15

1. Insulin glargine (Lantis)
2. Insulin detemir (Levemir)
3. Insulin glargine (Toujeo)