Lecture 2 - Lipids Part 1 Flashcards

(40 cards)

1
Q

what are the types of lipids

A

triacylglycerol

phospholipids

sphingolipids

sterols

fat soluble vitamins

etc

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2
Q

what is the most common type of lipid in our body and food

A

triglycerides

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3
Q

what are triglycerides a structural component in

A

lipoproteins

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4
Q

what is the major lipid class found in cell membranes

A

phospholipids

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5
Q

where is cholesterol found in the diet

A

animal products

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6
Q

important functions of cholesterol

A
  • structural component of membranes
  • steroid backbone
  • vitamin D
  • bile acids
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7
Q

what are the information molecules that fatty acids are an important component of

A

eicosanoids

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8
Q

what is a short chain fatty acid

A

C2-C6

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9
Q

what is a medium chain fatty acid

A

C8-C12

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10
Q

what is a long chain fatty acid

A

> C14

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11
Q

what are the melting points like of saturated fatty acids

A

high melting point = usually solid at room temperature

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12
Q

can the body synthesis saturated fatty acids

A

yes - so not essential in diet

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13
Q

what does C18 mean

A

18 carbons

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14
Q

what does the :0 mean in C18:0

A

no double bonds

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15
Q

what does a monounsaturated fatty acid have that saturated fatty acid doesnt

A

one cis or trans double bond

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16
Q

what are the melting points like of monounsaturated fatty acids

A

intermediate melting points

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17
Q

what are the melting points of polyunsaturated acids

A

low melting points

18
Q

can the body synthesise polyunsaturated acids

A

the body can not synthesise n-6 and n-3 PUFA so they are essential fatty acids

19
Q

what end do you count from in fatty acids

A

the methyl end

20
Q

what does C18:2n-6 mean

A

it has 18 carbons, two double bonds, the double bond is 6 away from the methyl end and then CH2 seperates the double bonds

21
Q

what carbon in fatty acids from the methyl end are humans unable to produce a double bond before

A

the 9th carbon, hence we must obtain fatty acids that have double bonds before the 9th carbon from the diet

22
Q

deficiencies in essential fatty acids can lead to ….

A
  • growth retardation
  • reproductive failure
  • skin lesions
  • kidney and liver disorders
  • neurological and visual problems
23
Q

what are examples of fats high in saturated fats

A
  • coconut oil
  • butter
  • beef tallow
  • palm oil
24
Q

what vegetable oils are rich in monounsaturated fatty acids

A
  • olive oil
  • canola oil
  • peanut oil
25
what are some vegetable oils are rich in polyunsaturated fatty acids
sunflower oil flaxseed oil etc
26
what omega will reduce your cholesterol the most
omega 6
27
what are the two ways that saturated fat increases cholesterol
- decrease LDL receptor activity - suppress ACAT (rate limiting enzyme of cholesterol esterification)
28
saturated fat causes ACAT to be suppressed, what does this cause
resulting in greater proportion of cholesterol remaining in the regulatory pool
29
what does trans fatty acids increase
cholesterol synthesis
30
what does PUFA (n-6) decrease
cholesterol
31
what does PUFA (n-3) decrease
TAG
32
how does PUFA (n-6) decrease cholesterol
- increase LDL receptor activity - increase CYP7 (rate limiting enzyme in converting cholesterol to bile acids)
33
how does PUFA (n-3) decrease TAG
decrease lipogenesis and VLDL secretion increase lipoprotein lipase activity increase reverse cholesterol transport
34
what omega is better for anti-inflammatory
omega 3
35
what % of dietary lipid is phospholipids
5-10% of dietary lipid
36
examples of information molecules (eicosanoids)
- Prostaglandins - Thromboxanes - Leukotrienes
37
do cis or trans double bonds have higher melting points
trans have higher melting points
38
example of saturated fat
stearic acid = C18:0
39
example of monounsaturated fat
oleic acid = C18:1n-9
40
example of polyunsaturated fat
linoleic acid = C18:2n-6