Flashcards in Lecture 26 + DLA 20 Deck (10)
What does Hardy- Weinberg assume?
1. population is large
2. random mating
3. no new mutations in the population
4. no migration of people into the population
What are factors that lead to genetic variation
1. new mutation
2. natural selection
3. genetic drift
What is an example of heterozygote advantage?
sickle cell disease
What is the Hardy-Weinberg equation?
p2 + 2pq + q2 = 1
What does p represent?
The functioning allele (homo)
What does q mean?
The disease causing allele (homo)
What group of people make up 2pq?
Carriers in the population
What is the founder effect?
A new mutation is presented into a small population by immigration or just a new mutation
What is genetic drift?
The allele may be lost or established by isolation of a population
especially if the population is small, the allele frequency may increase