Lecture 3 - Female Reproductive Tract I Flashcards Preview

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Flashcards in Lecture 3 - Female Reproductive Tract I Deck (20):
1

Fetal oocyte production?

as primordial germ cells in yolk sac, migrate to embryonic gonadal ridge @ 6weeks gestation

2

Germ cell development in ovary?

differentiation into diploid oogonia, population expands via mitosis producing oocytes, undergo meiosis up till prophase of meiosis I, lie completely dormant in ovarian cortex until puberty and beyond

3

Primordial -> tertiary follicle progression?

decreasing in numbers each step: primordial -> primary -> secondary (85 days) -> 1 or 2 tertiary (2-3 weeks)

4

identifying primordial cells?

flattened granulosa cells

5

identifying primary cells?

granulosa cells become cuboidal (follicular wave has begun)

6

Identifying secondary cells?

proliferation of g cells into multiple layers with FSH receptors which act to produces oestrogen, inhibin and AMH; thecal cell presence with LH receptors, acting produce androgen

7

Identifying tertiary cells?

antrum formation, w follicular fluid, theca externa development

8

Steroid pathway?

T cell turn progesterone to androgen, G cell turn androgen into oestrogen (all reversible)

9

Protein shell and cells?

zona pellucida, ZP1 (found in primordial), 2 and 3 added to activate follicle, filter normal sperm and prevent polyspermy

10

Cluster of cells surrounding oocyte within follicle?

cumulus oophorus

11

AMH?

anti-mullerian hormone, released from mature follicles to inhibit other primoridal development in follicular wave

12

FSH?

proliferates granulosa cells

13

Estrogen??

inhibits FSH, up till a peak where it positively feedsback as well as trigger LH spike causing ovulation

14

Progesterone?

produced by luteal granulosa cells (along with estrogen), moves from ovary to uterus to work on endometrium and myometrium

15

Inhibin?

negative feedbacks FSH @ pituitary

16

Parts of fllopian tubes?

fimbria, infundibulum, ampulla, isthmus

17

Lumen progression?

ampulla complex with heaps of foldings, wider as progresses

18

Epithelial lining?

ciliated or secretory, responsive to steroids (increased with oestrogen

19

Muscular coat and other component?

inner circular, outer long (serosal coat)

20

Hormone effects?

muscle activity, cilia, secretory activity; estrogen increases progesterone decreases