Lecture # 4 -exam1 Flashcards

1
Q

____________ in protein folding play a role in determining the final protein conformation.

A

Primary structures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Some proteins, even after heat denaturation, can _______

A

re-fold into their active conformation.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is the rate constant: enzyme

A

speed it becomes a product

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The rate constant of a reaction can be influenced by various factors.

A

temperature, adding enzymes, adding subtrates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Enzymes lower the _________, affecting the delta G of a reaction.

A

activation energy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

most enzymes require a

A

cofactor or coenzyme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

how do enzymes help?

A

limit movement to fit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Enzymes have certain characteristics, and some statements might not apply to them.

A

they are fit to spwecific substrates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

An increase in temperature can lead to an increase in___________

A

the rate constant of a reaction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

two rtpes of enzymes (specificity)

A

lock & key
induce fit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

_____ are essential for speeding up chemical reactions within cells.

A

Enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

If an inhibitor binds to the active site, it’s considered a _______

A

competitive inhibitor.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Methanol and ethanol can act as___________ of alcohol dehydrogenase.

A

competitive inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

skipp

skippp

A

skippp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Chaperone proteins assist in ____________ especially for those prone to misfolding.

A

proper protein folding,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Inhibitors can be matched with analogies that describe their action.

A

competitive: taking someones parking spot

16
Q

Beer, when used to treat methanol poisoning, acts as a__________

A

competitive inhibitor.

17
Q

Competitive inhibitors only bind to____________, not to those already bound to substrates.

A

free enzymes

18
Q

Noncompetitive inhibitors, similarly, only bind to __________

A

free enzymes

19
Q

Non-competitive inhibitors interfere with enzyme function by _________________

A

binding to sites other than the active site.

20
Q

two types of noncompetitive inhitors

A

noncomeptitive & allosteric

21
Q

How does noncompetitve & allosteric differ??

A

allosteric binds to free E & ES, nocompetitve only to ES