Lecture 6 Flashcards
Two types of gametes
- Ova (♀)
- Spermatozoa (♂)
Types of gametogenesis
- Spematogenesis
- Oogenesis
Phase of gametogenesis
- Origin of germ cell, migration to gonads
- Multiples of germ cells (mitosis)
- Reduction of the number of chromosmes by one half (meisosis)
- Final stages of maturation and differentiation.
Where can germplasm found in frogs and vertebrates
- in the vegetal pole cytoplasm of the zygote
Effect of UVR in germplasm
results in the development of an embryo lacking in germ cells
can be traced through cleavage (in cells near the vegetal pole) and into the endodermal floor of the primitive gut.
Germ-cell lineage
arise in the epiblast of early embryo
Primordial germ cells
Where can germinal cresent in bird be found
- region located beyond head of the embryo
where can posterior wall of the egg yoc sack in mammals be found?
- Near tehe region of the allantois
Where is the origin of germ cells in Urodele amphibian arises?
From embryonic mesoderm
Recognizable due to large size and clear cytoplasm
PGC
Histochemical characteristics of PGC in mammals, and birds?
- high alkaline phosphatase activity (mammals)
- high glycogen content (birds)
- monoclonal Antibodies (birds & mammals)
Two mechanisms in vertebrates where PGC migrats to gonads
- Through walls of blood vessels
- Around the wall of posterior gut and through dorsal mesentry
What are the extraceulluar matrix molecules that guide PGC migration
- Laminin and fibronectin
Once settled in the gonads, PGC enter _____
- increase their number by mitosis
Proliferative phase
When does intense mitotic activity of oogonia occur in human females, and how many are formed?
Between the 2nd–5th months of pregnancy
What happens to the number of oogonia after the 5th month in human females?
Atresia
a natural process of degeneration.
Atresia
What happens to oogonia by 7th month?
Enteres prophase of 1st meiotic division
How is oogenesis different in nonmammalian vertebrates compared to humans?
oogonia are capable of dividing throughout the reproductive cycle.
What happens to mitosis in rodents during early development?
continues in the gonad, but ceases during early days of pregnancy
How does mitosis function in human males starting from puberty?
in humans, it begins at puberty
Reproductive role of human male
produce and deliver sperm to the vagina
produce a fluid called
semen for carrying the sperm to the penis
Accessory glands