Lecture 8

Question 1

Skeletal Muscle has?

Answer 1

-Striated Pattern and Voluntary Movement
-3 Layers of CT

Question 2

Skeletal Muscle consists of 3 layers of CT?

Answer 2

-Epimysium
-Perimysium
-Endomysium

Question 3

Epimysium?

Answer 3

(dense irregular) Surrounds entire muscle

Question 4

Perimysium?

Answer 4

(dense irregular) Surrounds fasicle

Question 5

Endomysium?

Answer 5

(reticular) Surrounds individual fibers

Question 6

Muscle fibers are made up of?

Answer 6

Myofibrils (myofibrils are arranged in a parallel pattern that gives striations)

Question 7

Muscle Fibers consists of triads?

Answer 7

2 SR + 1 T-tubule (located at junction where A-Band meets I-Band) (SR stores calcium) (T-tubules initiate calcium release from SR into sarcomere)

Question 8

New muscle fibers are formed by?

Answer 8

Satellite Cells (satellite cells are only found in skeletal muscle)

Question 9

Red Muscle Fibers?

Answer 9

(Marathon)
-Rich vascular supply
-Slow and repetitive
-Not easily fatigued
-Weaker contraction
-Lot of Mitochondria so more ATP so more energy

Question 10

White Muscle Fibers?

Answer 10

(Sprint)
-Poorer vascular supply
-Fast
-Easily fatigued
-Stronger contraction
-Not a lot of Mitochondria so less ATP so less energy

Question 11

Skeletal Muscle - Sarcomeres?

Answer 11

Structural units of myofibrils

Question 12

Sarcomere Composition?

Answer 12

Actin (thin) + Myosin (thick)

Question 13

Function of Sarcomere?

Answer 13

Contraction of Skeletal Muscle

Question 14

A-Band?

Answer 14

Actin + Myosin; reminds same length during contraction

Question 15

H-Band?

Answer 15

Only Myosin; shortens in length during contraction

Question 16

I-Band?

Answer 16

Only Actin; shortens in length during contraction

Question 17

I-Band?

Answer 17

Only Actin; shortens in length during contraction

Question 18

Z-Disk?

Answer 18

Located on both sides of sarcomere to serve as boundaries

Question 19

Without ATP, skeletal muscle CANNOT?

Answer 19

Relax so it will stay contracted

Question 20

Skeletal Muscle -Contraction?

Answer 20

(An ATP-dependent process)
-Rigor Mortis
-Myasthenia Gravis
-Duchenne’s Muscular Dystrophy (MD)

Question 21

Rigor Mortis?

Answer 21

Continued contraction of muscle due to lack of ATP

Question 22

Myasthenia Gravis?

Answer 22

Antibodies target ACh receptor which prevents contraction

Question 23

Duchenne’s Muscular Dystrophy (MD)?

Answer 23

Dysfunctional Dystrophin Protein

Question 24

Neuromuscular Junction secretes?

Answer 24

ACh to stimulate T-tubules to release calcium from SR

Question 25

Neuromuscular Junction secretes?

Answer 25

ACh to stimulate T-tubules to release calcium from SR

Question 26

Titin?

Answer 26

Anchor thick to Z

Question 27

Tropomyosin and Troponin form?

Answer 27

Complex

Question 28

G-actin forms?

Answer 28

f-actin

Question 29

Extrafusal Fiber?

Answer 29

Skeletal Muscle Fiber

Question 30

Intrafusal Fiber?

Answer 30

Actual Reception (help to tell if extramural is contracting or relaxing)

Question 31

Cardiac Muscle has?

Answer 31

Striated pattern and involuntary movement

Question 32

Muscle cells consist of?

Answer 32

Diads (1 SR + 1 T-tubule) (located at z-disk) (lesser amount of SR so calcium is stored extracellularly) (T-tubules initiate calcium release from SR into sarcomere)

Question 33

Intercalated disks located?

Answer 33

Between cardiac muscle cells (composed of junctions (fascia adherent, desmosomes, gap junctions))

Question 34

Desmosomes bind?

Answer 34

Intermediate Filaments

Question 35

Fascia Adherent binds?

Answer 35

Actin

Question 36

Cardiac Muscle contains?

Answer 36

Endomysium (reticular CT surrounding muscle)

Question 37

Heart consists of 4 layers of tissue?

Answer 37

-Endocardium -Myocardium -Epicardium -Pericardium

Question 38

Endocardium?

Answer 38

Simple Squamous Epithelium lining Heart

Question 39

Myocardium?

Answer 39

Cardiac Muscle

Question 40

Epicardium?

Answer 40

Specialized CT (adipose)

Question 41

Pericardium?

Answer 41

Dense CT + Simple Squamous Epithelium

Question 42

Pericardium?

Answer 42

Dense CT + Simple Squamous Epithelium

Question 43

Smooth Muscle has?

Answer 43

Non-Striated patten and involuntary movement

Question 44

Non-striated means it has?

Answer 44

NO Sarcomeres

Question 45

Muscle Cells consists of?

Answer 45

Dense bodies + caveola

Question 46

Smooth Muscle Cells can regenerate without?

Answer 46

Satellite Cells

Question 47

There are 3 layers of smooth muscle?

Answer 47

-Muscularis mucosa -Muscularis externa (outer longitudinal layer) (inner circular layer)

Question 48

Dense bodies contain?

Answer 48

Alpha-actinin which functions as z-disk (alpha-actin = protein that binds actin)

Question 49

Caveola brings in calcium via?

Answer 49

Pinocytosis to initiate contraction (calcium is store extracellularly)

Question 50

Smooth and Cardiac Muscle store?

Answer 50

Extracellularly

Question 51

Skeletal Muscle stores?

Answer 51

Intracellularly