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Clinical Bacteriology (Midterm) > (Lecture) Neisseriaceae > Flashcards

(Lecture) Neisseriaceae Flashcards

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1
Q

Currently the genus Neisseria contains _____ and about _____ and biovars can be isolated from humans

A

25 species
12 species

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2
Q

Most Neisseria spp. are aerobic, nonmotile, non–spore-forming, gram-negative diplococci except _____, _____, and _____

A

Neisseria elongata
Neisseria weaveri
Neisseria bacilliformis

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3
Q

Neisseria species are oxidase positive or oxidase positive?

A

Oxidase positive

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4
Q

Most Neisseria species are catalase negative or catalase positive?

A

Catalase positive

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5
Q

Neisseria species are catalase positive except for _____ and _____ which are catalase negative

A

N. elongata
N. bacilliformis

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6
Q

Neisseria gonorrhoeae is often called _____

A

Gonococci

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7
Q

Neisseria meningitidis is often called _____

A

Meningococci

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8
Q

Neisseria gonorrhoeae and Neisseria meningitidis require _____ for growth

A

Iron

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9
Q

Agent for gonorrhea

A

Neisseria gonorrhoeae

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10
Q

Neisseria gonorrhoeae is also known as _____ from the French word clapoir meaning _____

A

Clap
Brothel

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11
Q

Neisseria gonorrhoeae Also known as “clap” from the French word _____ meaning “brothel”

A

Clapoir

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12
Q

An acute pyogenic infection of non-ciliated columnar and transitional epithelium and infection can be established at any site where the cells are found.

A

Gonorrhoeae

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13
Q

A sexually transmitted disease (STD) that can infect both men and women

A

Gonorrhea

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14
Q

Primary reservoir of Neisseria gonorrhoea:

A

Asymptomatic carrier

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15
Q

Incubation period of Neisseria gonorrhoeae:

A

2 to 7 days

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15
Q

Painful urination is also called _____

A

Dysuria

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16
Q

Most common clinical presentation of Neisseria gonorrhoeae in men is _____

A

Acute urethritis

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17
Q

Acute urethritis in men caused by Neisseria gonorrhoeae is characterized by _____ and _____

A

Purulent discharge
Dysuria

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18
Q

Most common site of infection in women for Neisseria gonorrhoeae is _____

A

Endocervix

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19
Q

Perihepatitis is also called _____

A

Fitz-Hugh-Curtis Syndrome

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20
Q

Blood-borne dissemination of Neisseria gonorrhoeae occurs in less than 1% of all infections, resulting in _____ and rarely _____

A

Purulent arthritis
Septicemia

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21
Q

Fever and rash on the extremities can also be present in blood-borne dissemination, because neisseria gonorrhoeae is inhibited by _____

A

Sodium Polyanethol Sulfonate or SPS

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22
Q

The anticoagulant for blood culture media

A

Sodium Polyanethol Sulfonate or SPS

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23
Q

A non-venereal infection is _____ in the newborn

A

Ophthalmia neonatorum

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24
Specimen of choice in the detection of Neisseria gonorrhoeae for genital infections in men and women:
Men: Urethra Women: Endocervix
25
In men, purulent discharge can be collected directly onto a swab for culture. When no apparent discharge is present, the swab is inserted up to _____ into the anterior urethra and slowly rotated to collect the material.
2cm
26
Swabs for rectal culture should be inserted _____ into the anal canal.
4 to 5cm
27
_____ and _____ are inhibitory to Neisseria gonorrhoeae, so ____ or _____ are preferred.
Calcium alginate Cotton swabs Dacron swabs Rayon swabs
28
Transport media for Neisseria gonorrhoeae
Amies medium with charcoal
29
Neisseria does not grow on what medium?
SBA
30
Medium of choice for Neisseria:
CAP
31
Selective medium for Neisseria:
1. Thayer-Martin 2. Modified Thayer-Martin 3. Martin-Lewis 4. New York City 5. GC-LECT
32
An inhibitory agent of Neisseria specie that inhibits gram-positive bacteria:
Vancomycin and Colistin
33
An inhibitory agent of Neisseria specie that inhibits Proteus spp.:
Trimethoprim
34
Incubation for Neisseria species:
Inoculated plates should be incubated at 35°C in a 3% to 5% CO2 atmosphere
35
Incubation is accomplished by use of a:
CO2 incubator CO2 generating pouch Candle extinction jar (white wax candles only)
36
Colony morphology of Neisseria spp on CAP:
Small, gray to tan, translucent, and raised after 24-48 hours of incubation
37
Traditional method for the identification of Neisseria spp.
Carbohydrate Utilization
38
Medium used for Carbohydrate Utilization in Neisseria gonorrhoeae:
Cystine Trypticase Agar containing 1% the individual carbohydrate and phenol red
39
An antibiotic that is recommended for the treatment Neisseria gonorrhoeae
Cephalosporin
40
Identify the disease based on the characteristics given: ● Purpura (hemorrhaging of blood into the skin and mucous membranes producing bruises) with petechial skin rash (pinpoint red spot caused by hemorrhage) ● Tachycardia ● Hypotension ● Thrombosis
Meningococcemia
41
Identify the disease based on the characteristics given: ● Frontal headache ● Stiff neck (nuchal rigidity) ● Confusion ● Photophobia ● 10-20% - neurologic complications or seizures
Meningitis
42
It is the hemorrhaging of blood into the skin and mucous membranes producing bruises
Purpura
43
Nuchal rigidity is also known as _____
Stiff neck
44
Hemorrhage in the adrenal glands is also known as _____
Waterhouse-Friderichsen Syndrome
45
Most Neisseria spp. are Gamma-glutamyl aminopeptidase positive except _____, _____, and _____
N. gonorrhoeae N. lactamica M. catarrhalis
46
Drug of choice for Meningitis
Penicillin
47
Drug of choice for Meningococcemia
Third generation cephalosporins
48
Drug of choice for close contact with patient positive for meningococcal disease
Chemoprophylaxis with rifampin or ciprofloxacin
49
Drug of choice for patients that are resistant to ciprofloxacin
Azithromycin
50
Most strains of moraxella catarrhalis can tolerate lower temperatures and grow well at _____
28 degree Celsius
51
Colony morphology of Moraxella on SBA and CAP:
Smooth, opaque, gray-to-white colonies “hockey puck” - colony remains intact when pushed across the plate with a loop
52
Older colonies of Moraxella may give a _____ appearance
"Wagon-wheel" appearance
53
Oxidase test result of Moraxella species:
Oxidase positive
54
Catalase test result of Moraxella species:
Catalase positive
55
DNAse test result of Moraxella species:
DNAse positive
56
Moraxella species are butyrate esterase (positive or negative).
Butyrate esterase positive
57
Identify Neisseria specie based on the given characteristics: - Misidentified as N. gonorrhoeae - Non-glucose fermenter - Grows on SBA - Susceptible to colistin
N. cinerea
58
Identify Neisseria specie based on the given characteristics: - Yellow-pigmented Neisseria species that is asaccharolytic
N. flavescens
59
Identify Neisseria specie based on the given characteristics: - Large, very mucoid colonies (often adhere to the agar)
N. mucosa
60
Identify Neisseria specie based on the given characteristics: - Glucose, maltose and lactose fermenter - Misidentified as N. meningitidis (glucose and maltose fermenter only)
N. lactamica
61
Identify Neisseria specie based on the given characteristics: - Produces large amounts of extracellular polysaccharide when grown in media containing 1% or 5% sucrose
N. polysaccharea
62
Identify Neisseria specie based on the given characteristics: - Dry, wrinkled, adherent, and breadcrumb-like colonies
N. sicca
63
"Sicca" in Latin means _____
Dry
64
Identify Neisseria specie based on the given characteristics: - “Less yellow”
N. subflava
65
Identify Neisseria specie based on the given characteristics: - Rod-shaped
N. elongata N. weaveri N. bacilliformis

Clinical Bacteriology (Midterm) (11 decks)

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