Lesson 1E (Part 1) Flashcards

1
Q

What are the types of thyroid gland diseases? (5)

A
  1. Hyperthyroidism
  2. Hypothyroidism
  3. Inflammatory/immune
  4. Goiter
    - adenoma (benign)
  5. Tumours
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2
Q

What are abnormal thyroid functions caused by? (3)

A
  1. Thyroid disease
  2. Disorders of the pituitary or hypothalamus
  3. Insufficient dietary iodine
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3
Q

What are the main effects of abnormal thyroid function caused by?

A

An abnormally high or low basal metabolic rate

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4
Q

What is another name for hyperthyroidism?

A

Thyrotoxicosis

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5
Q

What is hyperthyroidism?

A

Excessive levels of T3and T4

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6
Q

What are the main effects of hyperthyroidism due to?

A

Increased basal metabolic rate

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7
Q

What is a common consequence of an aging heart?

A

Cardiac failure

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8
Q

How does cardiac failure affect the heart?

A

The heart has to work harder to deliver more blood and nutrients to the hyperactive body cells

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9
Q

What does hyperthyroidism cause? (3)

A
  1. Graves’ disease
  2. Toxic nodular goiter
  3. Adenoma
    - a benign tumour
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10
Q

When does hypothyroidism occur?

A

When there is insufficient T3and T4secretion

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11
Q

What does hypothyroidism cause? (2)

A
  1. Congenital hypothyroidism in children

2. Myxoedema in adults

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12
Q

What is an another term for congenital hypothyrodism?

A

Cretinism

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13
Q

Cretinism

A

Profound deficiency or absence of thyroid hormones that becomes evident a few weeks or months after birth

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14
Q

Where is hypothyroidism and endemic?

A

In the parts of the world where the diet is severely deficient in iodine and contains insufficient for synthesis of T3and T4

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15
Q

What does the absence of thyroid hormones result in?

A

Profound impairment of growth and mental development

- unless treatment begins early

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16
Q

Why kind of impairments is there in cretinism? (5)

A
  1. Has disproportionately short limbs
  2. A large protruding tongue
  3. Coarse dry skin
  4. Poor abdominal muscle tone
    - rounded belly
  5. Umbilical hernia.
17
Q

What is myxoedema more common in? (2)

A
  1. The elderly
  2. Females
    - 5x more than men
18
Q

What does deficiency of T3and T4in adults result in?

A

An abnormally low metabolic rate

19
Q

What are the found causes for my myxoedema? (3)

A
  1. Autoimmune thyroiditis
  2. Severe iodine deficiency
  3. Healthcare interventions
    - e.g. antithyroid drugs, surgical removal of thyroid tissue or ionizing radiation
20
Q

What percent of graves disease are hyperthyroiditis?

21
Q

Who does graves disease affect the most?

A

Women

- between ages 30-50

22
Q

What kind of disorder is graves disease?

A

Autoimmune disorder

23
Q

Autoimmune disorder

A

Antibody that mimics the effects of TSH is produced

24
Q

Goitre

A

Visible enlargement of the gland

25
What stimulates thyroid growth?
Goitre
26
What is a sign of Graves' disease?
Exophthalmos
27
Exophthalmos
Abnormal protrusion of the eyeballs | - bulging
28
What kind of vascularity does greaves disease have?
High vascularity
29
What causes exophthalmos?
Due to the deposition of excess fat and fibrous tissue behind the eyes
30
What is another word for de quervains thyroiditis?
Subacute granulomatous thyroiditis
31
What is de quervain thyroiditis associated with? (3)
1. Hyperthyroidism 2. Hypothyroidism 3. Return to normal thyroid function
32
De quervains thyroiditis
Diffusely enlarged somewhat poorly marginated gland
33
What is colour doppler like with de quervains thyroiditis?
Normal or decreased - hard to tell the difference between this and graves (vascular is how you tell the difference --> graves is hypervascular)