Lesson 6 Flashcards

(62 cards)

1
Q

Is limiting the agent/pathogen’s access to people

A

Laboratory Biosafety

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2
Q

The containment principles, technologies and practices that are implemented to prevent the unintentional exposure to pathogens and toxins, or their accidental release.

A

Laboratory Biosafety

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3
Q

The protection, control, and accountability for valuable biological materials within laboratories, in order to prevent their unauthorized access, loss, theft, misuse, diversion, or intentional release.

A

Laboratory Biosecurity

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4
Q

Is limiting people’s access to the agent/pathogen.

A

Laboratory Biosecurity

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5
Q

Date:
First scientific director of ______ (Fort Detrick)

A

Date: 1943
Ira L. Baldwin, Camp Detrick

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6
Q

Date:
US President Franklin Roosevelt tasked Baldwin to establish __________ for defensive purposes during the Cold War

A

Date: 1943
US biological weapons program

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7
Q

Date:
The biological weapons program was terminated by US President _______

A

Date: 1969
Richard Nixon

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8
Q

After the Second World War, Camp Detrick was designated a permanent installation for _________

A

Biological research and development.

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9
Q

Date:
Began of the _______ of smallpox

A

Date: 1967
Intensified Eradication Program

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10
Q

Designed modifications for biosafety at
Camp Detrick

A

Newell A. Johnson

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11
Q

Date:
Formation of _______ (ABSA)

A

Date: 1984
American Biological Safety Association

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12
Q

Date:
England and South Africa either destroyed the stocks or transferred them to other approved labs. Therefore, only two locations
where variola virus is officially stored.

A

Date: 1984
Center for Disease Control and Prevention (CDC)
State Research Center of Virology and Biotechnology VECTOR (SRCVB VECTOR)

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13
Q

Date:
The ________ agreed to reduce the number of laboratories holding stocks of _____ virus (United States, England, Russia, and South Africa)

A

Date: 1967
World Health Assembly, Variola Virus

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14
Q

Published by ______ , and introduced the concept of establishing ascending levels of containment associated with risks in handling groups of infectious microorganisms that present similar
characteristics

A

Classification of Etiologic Agents on the Basis of Hazard

Published by: CDC

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15
Q

Explained in detail the microbiological practices, equipment, and facility necessarily corresponding to four ascending levels of physical containment

A

NIH Guidelines for Research Involving Recombinant DNA Molecules

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16
Q

Date:
Laboratory Biosafety Manual

A

Date: 1983
Laboratory Biosafety Manual

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17
Q

Date:
Marked the development of the practice of laboratory biosafety

A

Date: 1984
Biosafety in Microbiological and Biomedical Laboratories

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18
Q

Date:
Established the model of biosafety containment levels with certain agents which increased the biosafety levels for biological agents that
pose risk to human health.

A

Date: 1984
Biosafety in Microbiological and Biomedical Laboratories

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19
Q

Director of_______; recognized as one of the pioneers of biosafety

A

Arnold Wedum, Industrial Health and Safety

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20
Q

Ensures that the proper equipment and facility controls are in place based on the specified biosafety level of the laboratory.

A

Biosafety Officers

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21
Q

Together with Wedum, analyzed multiple epidemiological studies of laboratory-based outbreaks

A

Morton Reitman

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22
Q

Date:
Members of the ___________ commune purchased a strain of _______ from a medical supply company in Seattle, Washington

A

Date: 1980
Rajneeshee, Salmonella

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23
Q

Date:
At least 5 envelopes containing _____________ were mailed to US senators and media organizations

A

Date: 2001
(Amerithrax) Bacillus anthracis spores (etiologic agent of anthrax)

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24
Q

(USAMRIID)

A

United States Army Medical Research Institute for Infectious Disease

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25
Through rats containing flea; causes bubonic plague
Yersinia pestis
26
Causes cholera through contaminated water or food
Vibrio cholerae
27
Causes tularemia through ticks
Francisella tularensis
28
Date: To monitor the transfer of a select list of biological agents from one facility to another
Date: 1996 Select Agent Regulations
29
(Singapore)
Biological Agents and Toxins Act
30
(South Korea)
Act on Prevention of Infectious Diseases
31
(Japan)
Infectious Disease Control Law
32
Regional professional society for biosafety and biosecurity founded in _____
Date: 1984 American Biological Safety Association (ABSA)
33
Promotes biosafety as a scientific discipline and provides guidance to its members on the regulatory regime present in North America
American Biological Safety Association (ABSA)
34
Date: Group founded in _____ that acts as a professional society for biosafety professionals in the Asia-Pacific region.
Date: 2005 Asia-Pacific Biosafety Association (A-PBA)
35
Active members of the International Biosafety Working Group are required to directly contribute to the development of the best biosafety practices
Asia-Pacific Biosafety Association (A-PBA)
36
Date: A non-profit organization founded in ___ Aims to provide a forum for discussions and debates on issues of concern and to represent those working in the field of biosafety.
Date: June 1996 European Biological Safety Association (EBSA)
37
Focuses on encouraging and communicating among its members information and issues on biosafety and biosecurity as well as emerging legislation and standards
European Biological Safety Association
38
Non-government and non-profit association that works to serve the emergent concerns of biological risk management in various professional fields such as in the health, agriculture, and technology sectors throughout the country
Biological Risk Association Philippines
39
Tag line of BRAP
Assess Mitigate Monitor
40
An environmental health engineer working for the Dow Chemical Company containment systems products
Charles Baldwin
41
Created the _______ symbol used in labeling biological materials carrying significant health risks.
Charles Baldwin, Biohazard symbol
42
Classification of Microorganisms (WHO)
✓ Agent’s pathogenicity ✓ Mode of transmission ✓ Host range ✓ Availability of preventive measures and effective treatment
43
No or low individual and community risk
Risk group 1
44
Includes microorganism, or material containing microorganisms, that are already present in the environment, and are unlikely to cause human, plant, or animal disease, disrupt a region or an industry.
Risk group 1
45
Moderate individual risk, and low/limited community risk
Risk group 2
46
Includes microorganism, or material containing microorganisms, that can cause human, plant, or animal disease, but is unlikely to be a serious hazard to laboratory workers, community, livestock, or the environment.
Risk group 2
47
High individual risk, and limited to moderate community risk
Risk group 3
48
Includes microorganism, or material containing microorganisms, that usually causes serious human, plant, or animal disease, and may present a serious risk to laboratory workers.
Risk group 3
49
It could present a risk if spreads in the community, in a region, to the livestock industry or the environment, but there are usually effective preventive measures or treatment available.
Risk group 3
50
High individual and community risk
Risk group 4
51
Includes microorganism, or material containing microorganisms, that are known to produce life-threatening diseases to humans or animals.
Risk group 4
52
It represents a significant risk to laboratory workers and may be readily transmissible from one individual to another; effective treatment and preventive measures are not usually available.
Risk group 4
53
CDC categorized laboratories based on:
✓ Design features and construction ✓ Containment facilities ✓ Equipment ✓ Practices ✓ Operational procedures
54
Suitable for work involving viable microorganisms that are known not to cause disease in humans.
Biosafety level 1
55
Basically designed for laboratories that deal with indigenous moderate-risk agents present in the community.
Biosafety level 2
56
It is most appropriate among undergraduate and secondary educational training and teaching laboratories
Biosafety level 1
57
It observes practices, equipment, and facility design that are applicable to clinical, diagnostic, and teaching laboratories consequently observing good microbiological techniques.
Biosafety level 2
58
It is appropriate when work is done with human blood, body fluids, tissues, or primary human cell lines where there is uncertain presence of infectious agents.
Biosafety level 2
59
All procedures where infectious aerosols or splashes may be created are conducted in biosafety cabinets or other physical containment equipment.
Biosafety level 2
60
Designed for laboratories that deal with indigenous or exotic agents with a potential for respiratory transmission, and that may cause serious and potentially lethal infection.
Biosafety level 3
61
Laboratory required when working with dangerous and exotic agents that pose high individual risks of life-threatening diseases that may be transmitted via the aerosol route, for which there are no available vaccines or treatment.
Biosafety level 4
62
The laboratory worker’s complete isolation from aerosolized infectious materials is accomplished primarily by working in a Class III biosafety cabinet or in a full-body, air-supplied positive-pressure personnel suit
Biosafety level 4