Limjoco 2

Question 1

Hilar location of this tumor will cause symptoms of biliary obstruction (Klatskin tumor)

Answer 1

Cholangiocarcinoma

Question 2

Elevated serum CA19-9

Answer 2

Cholangiocarcinoma

Question 3

Firm, gray-white tumor

Answer 3

Cholangiocarcinoma

Question 4

Disorderly tubular glands in sclerotic stroma

Answer 4

Cholangiocarcinoma

Question 5

Difficult to diagnose and treat. Can cause biliary obstructive symptoms. Do surgical resection if possible (whipple’s procedure). Transplant if liver is resected

Answer 5

Cholangiocarcinoma

Question 6

Most common primary sarcoma of the liver

Answer 6

Angiosarcoma

Question 7

Primary malignant pediatric liver cell tumor. Most common primary liver tumor of childhood

Answer 7

Hepatoblastoma

Question 8

Hepatoblastoma is ___ if not treated

Answer 8

Fatal

Question 9

Associated with beckwith-wiedemann syndrome and FAP

Answer 9

Hepatoblastoma

Question 10

Epithelial type of ______ has best prognosis

Answer 10

Hepatoblastoma

Question 11

Cords of small hepatocytes. Light and dark herringbone pattern

Answer 11

Fetal epithelial type hepatoblastoma

Question 12

Can be associated with extrahepatic disease. Elevated AFP.

Answer 12

Hepatoblastoma

Question 13

With hepatoblastoma, if AFP is low/normal, it is

Answer 13

More aggressive

Question 14

May be caused by drugs to maintain a low birth weight infant

Answer 14

Hepatoblastoma

Question 15

Treat ________ with chemo and surgical resection

Answer 15

Hepatoblastoma

Question 16

Colon, breast, lung, and pancreas

Answer 16

Liver mets

Question 17

Neuroblastoma, Wilms tumor, and rhabdomyosarcoma

Answer 17

Children liver mets

Question 18

___________ most common cause of jaundice in pregnancy

Answer 18

Viral hepatitis

Question 19

Toxemia of pregnancy

Answer 19

Eclampsia

Question 20

Elevated aminotransferases, ALP, and bilirubin

Answer 20

Preeclampsia and eclampsia

Question 21

Periportal sinusoidal deposits of fibrin. Coagulative hepatocyte necrosis

Answer 21

Preeclampsia and eclampsia

Question 22

Hemolysis, elevated liver enzymes, low plts

Answer 22

HELLP syndrome

Question 23

Multisystem d/o that presents in last trimester with RUQ pain, N/V, and edema

Answer 23

HELLP syndrome

Question 24

Periportal sinusoids with fibrin and hemorrhage in space of Disse

Answer 24

HELLP syndrome

Question 25

Seen in third trimester. Defects in mitochondrial FA beta-oxidation. Can have mild changes (elevated serum transaminases) or liver failure, coma, and death.

Answer 25

Acute fatty liver of pregnancy

Question 26

May be due to coexistent preeclampsia

Answer 26

Acute fatty liver of pregnancy

Question 27

Microvesicular steatosis, scant inflammation and necrosis

Answer 27

Acute fatty liver of pregnancy

Question 28

Seen in third trimester of multiparious women. Hx of Cholestasis with OC use. Pruritus

Answer 28

Intrahepatic cholestasis of pregnancy

Question 29

Pruritus, jaundice, darkening urine, and lightening stools. Conjugated hyperbilirubinemia, ALP elevated. Bile salts markedly increased

Answer 29

Intrahepatic cholestasis of pregnancy

Question 30

Mutations in phospholipid translocation, ATP cassette transporter B4

Answer 30

Intrahepatic cholestasis of pregnancy

Question 31

Biliary defects in secretion of bile salts or sulfated progesterone metabolites

Answer 31

Intrahepatic cholestasis of pregnancy

Question 32

Benign. But increased fetal distress, still births, and prematurity

Answer 32

Intrahepatic cholestasis of pregnancy

Question 33

Second most common malignant primary hepatic tumor. Arises from ducts within and outside liver. Incidence increased 3X in 70's-90's

Answer 33

Cholangiocarcinoma