Lipid metabolism

Question 2

The most abundant lipid in diet

Answer 2

Triacylglycerol

Question 3

Bile salts are synthesized from what in the liver?

Answer 3

Cholesterol

Question 4

An example of bile salt mentioned in the slides

Answer 4

Taurocholic acid

Question 5

After absorption of free fatty acids and 2-monoacylglycerol by the epithelial cells they are converted to……. and packaged as…….

Answer 5

Triacylglycerol
Chylomicrons

Question 6

What inhibits lipolysis by blocking lipase access to TAG’s?

Answer 6

Perilipin

Question 7

What is the initiating lipase in lipolysis?

Answer 7

ATGL( Adipose Triglyceride lipase

Question 8

The second lipase in lipolysis is

Answer 8

HSL ( hormone sensitive lipase)

Question 9

What reaction do we have fatty acids being converted to acetyl CoA

Answer 9

Beta- oxidation

Question 10

Fatty acids with carbon chain length greater than 12 are transported into the mitochondrial matrix using which shuttle?

Answer 10

Carnitine shuttle

Question 11

Which enzyme is used to activate fatty acids?

Answer 11

acyl-CoA synthetase

Question 12

Which part of the membrane is acyl-CoA synthetase found?

Answer 12

Outer Mitochondrial matrix

Question 13

What commits the fatty-acyl CoA to the oxidative fate?

Answer 13

When it is converted to a carnitine ester

Question 14

The successive removal of two-carbon units in the form acetyl-CoA from fatty acids is known as

Answer 14

Beta-oxidation

Question 15

Which side of the fatty acyl chain does beta-oxidation start from?

Answer 15

The carbonyl end

Question 16

Function of CPT I

Answer 16

Converts fatty acyl-CoA to acyl- carnitine

Question 17

Function of CPT II

Answer 17

Converts acyl-carnitine to fatty acyl-CoA