Ketosis

Question 1

know the enzyme inhibited by statins

Answer 1

& alpha hydrolase, cholesterol

Question 2

What is Ketosis?

Answer 2

The synthesis of ketone bodies from acetyl CoA in the absence of sufficient carbohydrates

Question 4

The three ketone bodies

Answer 4

Acetone
Acetoacetate
Beta-hydroxybutyrate

Question 5

Which ketone body is not utilized by cells?

Answer 5

Acetone

Question 6

What causes ketosis?

Answer 6

Increased level of acetoacetate and beta-hydroxybutyrate
Diabetes mellitus
Starvation (low calorie intake)

Question 8

Which enzyme commits HMG-CoA to ketone body formation?

Answer 8

HMG-CoA lyase

Question 9

The oxidative phase of PPP is needed for cholesterol synthesis

Question 10

Which enzyme is inhibited by statins?

Answer 10

HMG-CoA reductase

Question 11

What causes familial hypercholesterolemia?

Answer 11

Defect in LDL receptor or apo B-100

Question 12

Which key enzyme converts cholesterol to bile salts?

Answer 12

7 apha- hydroxylase

Question 13

Steroid hormones are synthesized from?

Answer 13

Cholesterol

Question 14

The function of glucocorticoids

Answer 14

Regulate gluconeogenesis and reduce the inflammatory response

Question 15

Function of Mineralcorticoids

Answer 15

Control the reabsorption of inorganic ions by the kidney

Question 16

Examples of steroid medications

Answer 16

Cortisone
Prednisolone

Question 18

Organs in the body that utilize ketone bodies

Answer 18

Kidneys (renal cortex)
Brain
Skeletal muscles
heart muscles