Lipids Flashcards

1
Q

Transported in CHYLOMICRONS

A

LONG CHAIN FA

C16

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2
Q

Directly absorbed in the bloodstream – HEPATIC PORTAL VEIN

A

Medium Chain FA

C8-C14

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3
Q

Directly absorbed in the bloodstream – HEPATIC PORTAL VEIN

FOOD for the COLONOCYTES

A

Short Chain Fatty Acids

C2-C6

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4
Q

NO DOUBLE BOND in the hydrocarbon chain

fatty is saturated with HYDROGEN

all C-C bonds are SINGLE BONDS

A

SATURATED FA

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5
Q

At least ONE DOUBLE BOND in the hydrocarbon is present

A

UNSATURATED FA

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6
Q

H atoms found on the SAME side

A

CIS form

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7
Q

H atoms found on the OPPOSITE side

A

TRANS FORM

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8
Q

ONLY 1 DOUBLE BOND

A

Monounsaturated FA

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9
Q

MORE THAN 1 DOUBLE BOND

A

Polyunsaturated Fatty Acids

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10
Q

ESSENTIAL FATTY ACIDS

A

Linoleic Acid

a- linolenic acid

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11
Q

SEMI ESSENTIAL FATTY ACIDS

A

Arachidonic acid – from linoleic acid

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12
Q

Omega 3 FA

A
alpha linolenic acid
timnodonic acid (eicosa pentaenoic acid)
cervonic acid (docosa hexaenoic acid) (DHA)
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13
Q

Omega 6 series

A
Linoleic acid
Linolenic acid (GLA)
Arachidonic acid
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14
Q

Omega 9 series

A

Oleic acid

Elaidic acid

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15
Q

SIMPLE LIPIDS

A

FA + glycerol

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16
Q

COMPLEX LIPIDS

A

FA + (glycerol/sphingosine) + phosphoric acid/carbohydrates/proteins

17
Q

Docosa Hexaenoic Acid (DHA)

A

SOURCES: human milk, fish liver oils, algal oils

synthesized in the body from alpha linolenic acid

HIGHEST CONCENTRATION - RETINA, CEREBRAL CORTEX, SPERM

18
Q

Associated with LOW DHA

A

INCREASED RISK OF RETINITIS PIGMENTOSA

19
Q

Main storage form of lipids in the body

A

TRIACYLGLYCEROL (Triglyceride, neutral fat)

20
Q

Glycerophospholipid Components

A

Glycerol
FA esterified to the first 2 carbon atoms
Nitrogenous base
Phosphoric Acid

21
Q

Components of Phosphatidic Acid

SIMPLEST PHOSPHOLIPID

A

Glycerol
FA esterified to the first 2 carbon atoms
Phosphoric Acid

22
Q

Most abundant phospholipid of cell membrane

LARGEST BODY STORE OF CHOLINE

A

LECITHIN (Phosphatidylcholine)

23
Q

Glycerophospholipid w/ Ethanolamine as nitrogenous base

Play role in BLOOD COAGULATION

A

Cephalin (Phosphatidyl Ethanolamine)

24
Q

ONLY phospholipids which possess ANTIGENICITY

A

CARDIOLIPIN

recognized by antibodies raised against T. pallidum (syphilis)

25
Nitrogenous base - SERINE Plays an important role in PROGRAMMED CELL DEATH
Phosphatidylserine
26
Present in the CELL MEMBRANE Play an important role in CELL SIGNALLING and MEMBRANE TRAFFICKING Precursor of 2nd messenger in hormonal pathways
Phosphatidylinositolr
27
Found in OUTER LEAFLET OF CELL MEMBRANE BILAYER Abundant in LIPID RAFTS and MYELIN SHEATH Play a role in cell signalling and apoptosis
Sphingomyelins
28
Complex lipids which contain carbohydrate but NO phosphoric acid
GLYCOLIPIDS Cerebroside Globoside Ganglioside
29
Ceramide + Monosaccharide
CEREBROSIDE Glucocerebroside - ceramide + glucose Galactocerebroside - ceramide + galactose
30
Ceramide + Oligosaccharide
Globoside
31
Ceramide + Oligosaccharide with NANA or sialic acid
Ganglioside
32
The simplest ganglioside found in tissues
GM3 ganglioside ceramide + glucose + galactose + NANA
33
Known to be receptor for CHOLERA TOXIN in human intestine
GM 1 Ganglioside
34
FA required in the diet d.t. inability of human cells to synthesize
Essential FA
35
Refers to the location of sites of UNSATURATION relative to the omega end
Omega Fatty Acid
36
FA with a single site on unsaturation
MONOUNSATURATED FA (MUFA) Oleic acid - omega 9 MUFA - most physiologically significant MUFA
37
FA with a multiple sites of unsaturation
POLYUNSATURATED FA (MUFA) omega 3 and omega 6 PUFA