Topnotch Final Exam Flashcards
(28 cards)
Essential AA
NOT synthesized by the body
PVT TIM HaLL
Phenyalanine Valine Tryptophan Threonine Isoleucine Methionine Histidine Leucine Lysine
Semi Essential AA
Conditionally essential
needed in extra amount during GROWTH and DEVT of CHILDREN
Arginine
Non Essential AA
Synthesized by the body
skeletal changes vascular changes ectopic lens (upward, outward)
FIBRILLIN - scaffold for elastin synthesis
Marfan Syndrome (AD)
hyperextensible skin
hypermobille joint
easy bruisability
COLLAGEN (type III - MC affected)
Ehlers Danlos Syndrome (AD)
Villefranche Classification of Ehlers Danlos Syndrome
HYPERMOBILITY
Type III collagen
Tenascin X
MC subtype
Villefranche Classification of Ehlers Danlos Syndrome
CLASSICAL
Type V collagen
Villefranche Classification of Ehlers Danlos Syndrome
VASCULAR
Type III collagen
deadliest; most lethal
Villefranche Classification of Ehlers Danlos Syndrome
KYPHOSCOLIOSIS
Lysylhydroxylase
Villefranche Classification of Ehlers Danlos Syndrome
ARTHROCHALASIS
Type I collagen
Villefranche Classification of Ehlers Danlos Syndrome
DERMATOSPARAXIS
ADAMTS2
IMPORTANT GAGs
cell migration during morphogenesis and repair
Hyaluronic Acid
IMPORTANT GAGs
major component of CARTILAGE
Chondroitin sulfate
IMPORTANT GAGs
isolated in CORNEA
Keratan sulfate I
IMPORTANT GAGs
isolated in CARTILAGE
Keratan sulfate II
IMPORTANT GAGs
anticoagulant
found mainly in MAST CELLS
Heparin
IMPORTANT GAGs
found in KIDNEY BASEMENT MEMBRANE along w/ TYPE IV collagen
Heparan sulfate
IMPORTANT GAGs
main GAG of the SKIN
Dermatan
IMPORTANT GAGs
most ABUNDANT GAG in BODY
Chondroitin sulfate
Pentose Phosphate Pathway
LOCATION
Cytosol
Pentose Phosphate Pathway
RATE LIMITING STEP
G6P dehydrogenase
Pentose Phosphate Pathway
ATP USED/FORMED
NONE
Pentose Phosphate Pathway
GOALS
source of NADPH (for reduction)
generate PENTOSES
Pentose Phosphate Pathway
LOCATION IN THE BODY
RBC, lens
liver, adipose tissue, adrenal cortex, gonads, lactating mammary glands
