lipids Flashcards

(82 cards)

1
Q

main function of lipids

A

energy

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2
Q

fats, oils , phospholipids , steroids and carotenoids are all considered wt ?

A

lipids

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3
Q

lipids dissolve in water ?

A

they dont dissolve

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4
Q

Fatty acids are found in two main places

A

fats and phospholipids

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5
Q

wt do fatty acids do in the phospholipids

A

These build the walls of your cells (called cell membranes)

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6
Q

palmitic acid and stearic acid are saturated or unsatured ?

A

saturated

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7
Q

oleic acid, linoleic acid , a-linolenic acid and arachidonic acid are saturated or non saturated ?

A

non saturated

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8
Q

which fatty acids are solid and which is liquid ?

A

saturated fatty acids are solid and unsaturated are liquid

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9
Q

Plants & Bacteria Make all fatty acids from

A

acetyl-CoA.

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10
Q

Types of Essential Fatty AcidsOmega-6

A

Omega-6 and omega 3

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11
Q

Linoleic acid is an example of which omega ?

A

6

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12
Q

α-Linolenic acid is an example of which omega

A

3

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13
Q

who is involved in inflammation & immunity.

A

Omega-6: Linoleic acid

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14
Q

who is involved in cardioprotective.

A

omega 3

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15
Q

Health Benefits of Omega-3 & 6:

A

↓ Triacylglycerols

↓ Blood pressure

↓ Platelet aggregation (less clotting)

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16
Q

High levels of triacylglycerols can increase the risk of wt ?

A

heart disease

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17
Q

fatty acids react with alcohol to form wt ?

A

esters

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18
Q

hydrogenation wdym ?

A

Unsaturated Fatty Acids , they have double bond u can add hydrogen to remove the bond

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19
Q

wt happens during hydrogenation

A

We try to turn liquid oils (unsaturated) into solid fats (like margarine) but sometimes instead of removing th double bond the shape of the bond changes from cis to trans.

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20
Q

acylation

A

Some proteins have fatty acids stuck to them

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21
Q

wt helps the protein to stick to the cell membrane

A

The fat

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22
Q

Myristoylation adds wt ?

A

myristic acid

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23
Q

Palmitoylation adds wt ?

A

palmitic acid

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24
Q

Eicosanoids

A

They are messenger molecules made from fatty acids.

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25
3 Main Types of Eicosanoids
Prostaglandins Thromboxanes Leukotrienes
26
causes pain, fever, inflammation which Eicosanoids
Prostaglandins
27
help blood clot which Eicosanoids
Thromboxanes
28
cause allergy and asthma effects which Eicosanoids
Leukotrienes
29
autocrine is an example of wt ?
Eicosanoids
30
Eicosanoids They are mostly made from
Arachidonic acid (ω-6 fatty acid) Eicosapentaenoic acid (EPA) (ω-3 fatty acid)
31
fats are solid or liquid
solid and have a high staurated fatty acid
32
Why Triacylglycerols Are Better Energy Storage Than Glycogen
1- they take up less space and has more energy
33
Wax Esters are made of
Long-chain fatty acid + Long-chain alcohol → Wax ester
34
carnuba example of wt ?
wax ester
35
wt are the two types of phospholipids
phosphoglycerides and sphingomyelins
36
phosphatidic acid and phosphoglyceride . wts the diff ?
phosphatidic acid has no alcohol
37
phosphatidylinositol wt is it ?
It’s a phosphoglyceride that contains Inositol (a sugar alcohol)
38
GPI anchor function
connects certain proteins to the outer surface of the cell membrane.
39
The GPI anchor is made of:
Phosphatidylinositol (the fat in the membrane) A sugar chain A linker that ties the protein to the anchor
40
What are Phospholipases
They are enzymes (tiny scissors) that cut phospholipids (fats in the membrane).
41
hydrolyse the ester bonds at C1 and C2 of glycerol, respectively.
Phospholipases A1 (PLA1) and A2 (PLA2)
42
can hydrolyse both the C-1 and the C-2 ester bonds
Phospholipase B (PLB)
43
are phosphodiesterases that yield diacylglycerol and phosphatidic acid, respectively.
Phospholipases C (PLC) and D (PLD)
44
emulsification
Bile salts break big fat globules into tiny droplets
45
PLA₂ enzyme
It destroys your cells,
46
q PLA₂ enzyme causes
Dead muscles Nerve damage Red blood cells to burst
47
Bacteria (Clostridium perfringens) Causes
gas gangrene (your tissue dies and swells with gas
48
Bacteria (Clostridium perfringens) makes a toxin called
α-toxin
49
a toxin , wt does it do
This melts cells, so the bacteria can spread
50
They are a type of lipid (fat) found in cell membranes of animals and plants.
Sphingolipids
51
Tay-Sachs Disease cause by which enzyme
β-hexosaminidase A
52
wt happens in tayy sachs
This enzyme normally breaks down GM2 ganglioside (a type of sphingolipid).
53
They are a large group of molecules made of repeating units of isoprene (which has 5 carbon atoms)
Isoprenoids (also called terpenoids
54
Monoterpenes where do we find it ?
Perfumes, essential oils
55
Sesquiterpenes where do we find it
Citronella (mosquito repellent)
56
Tetraterpenes where do we find it ?
Carotenoids (like in carrots)
57
Monoterpenes name
b-carotenoids
58
Mixed terpenoids consist of
nonterpene group attached to the isoprenoid group
59
vitamin K and vitamin E are an example of wt terepnoid
mixed
60
proteins are covalently attached to special lipid groups called
prenyl groups.
61
Two common types of prenyl group
Farnesyl group (15 carbons = 3 isoprenes) Geranylgeranyl group 20 carbons = 4 isoprenes)
62
Steroids made from
triterpenes6 isoprene units = 30 carbons
63
Cholesterol used to make wt ?
Hormones (like estrogen & testosterone) Vitamin D Bile salts (for digestion)
64
Steroids differ based on:
Where the double bonds are What groups are attached (e.g., OH, CH₃)
65
Cardiac Glycosides
steroid-like molecules that affect the heart.
66
Cardiac Glycosides wt do they do ?
they increase heart muscle contraction — helpful in heart failure.
67
Ouabain effect
very toxic - blocks a key pump
68
Digitalis (and Digitoxin) effect
Used as medicine for weak heart
69
the body wraps the fats in wt to travel in blood
lipoproteins
70
The protein part in lipoprotein wt do we call it ?
apolipoprotein
71
which lipoprotiens are the biggest and least dense
chylomicrons
72
chylomicrons made where
intestine
73
Chylomicrons carry
Carry triacylglycerols & cholesteryl esters from food to tissues
74
vldl is made where
in the liver
75
vldl carry wt ?
lipids to tissues
76
vldl turn into wt s they lose fat ?
ldl
77
which lipoportien in called bad cholestrol
LDL
78
which lipoprotein is called good cholestrol
HDL
79
which lipoprotein cleans up extra cholestrol from blood and tissues and takes it back to the liver
HDL
80
HDL Uses an enzyme called
LCAT
81
LCAT function
collect and package cholesteryl estersand then hdl delivers them to the liver aand turns them into bile acids
82
removes extra cholesterol = protects your heart. who ?
HDL