nuc acids Flashcards

(55 cards)

1
Q

who makes the backbone of the DNA ?

A

phosphate groups

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2
Q

each phosphate can bind to maximum amount of water

A

6 water molecules

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3
Q

wt prevents the DNA phosphate group from repelling each other ?

A

water
magensium ions
proteins like histones

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4
Q

water , magnesium and histone how does it affect the DNA ?

A

makes it less shaky and more stable

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5
Q

transversion mutation is caused by wt ?

A

radiation ot chemicals

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6
Q

transition mutation caused by ?

A

deamination ( a chemical change inside the base )

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7
Q

wt happens in framshift mutation ?

A

adding or deleting 1 or 2 letters changes everything

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8
Q

wdwm by repeat expansion mutation

A

a small sequence of DNA is repeated many times accidentally

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9
Q

expansion mutation causes wt ?

A

huntingtons disease

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10
Q

deamination meaning ?

A

removing an amino group

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11
Q

ROS induced oxidative wdwm ?

A

reactive oxygen can damage DNA

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12
Q

which DNA happerns when theres humid ?

A

B DNA

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13
Q

which dna looks like a right hand spiral ?

A

B dna

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14
Q

which DNA is the dry version ?

A

A-DNA

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15
Q

a right hand spiral but very tight which dna ?

A

A DNA

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16
Q

forms like a left hand spiral ?

A

Z DNA

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17
Q

which DNA forms during transcription

A

Z dna

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18
Q

who forms as a result in torision ?

A

Z DNA

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19
Q

Prokaryotes chromosome is a wt dna ?

A

circular

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20
Q

in bacteria the DNA is found where ?

A

nucleoid

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21
Q

what should happen to the dna of bacteria to fit in the small cell

A

it needs to be compacted

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22
Q

large DNA are compactedby who

A

nucleoid associated proteins

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23
Q

which dna is bigger eukaryotic dna or prokaryotic dna ?

A

eukaryotic dna is much bigger

24
Q

each chromosome is wrapped around proteins called ?

25
DNA + PROTEINS FORM WT ?
CHROMATIN
26
wt are histones ?
are proteins that help DNA compact into chromatin
27
wt are the five major classes of histones ?
H1 , H2A , H2B , H3 , H4
28
WHICH histone sits outside the bead helping to lock the dna in place and link one nucleosome to the next ?
H1
29
instructions for making proteins and RNA
genome
30
genome is simple and circular dna who ?
prokaryotes
31
genome more complex and linear dna
eukaryotes
32
involved in protein synthesis and plays a structural and enzymatic roles as well who ?
RNA
33
which one is more stable RNA wala DNA ?
DNA
34
rna has wt sugar ?
ribose sugar
35
wt makes RNA more reactive than dna ?
the presence of the 2 oh group of ribose
36
in RNA wt is replaces instead of thymine ?
uracil
37
rna is single or double strand ?
single strand
38
can RNA cleave ?
YES
39
trna function
transports amino acids to ribosomes
40
look like a wraped cloverleaf due to extensive intrachain base pairing who ?
TRNA
41
AMINO acids are attached via wt ?
aminoacyl- TRNA synthestases
42
who attaches the correct amino acid to the corresponding TRNA ?
AMINO ACYL TRNA
43
a sequence of these nucleotides on the trna
anticodon
44
a sequence of these nucleotides on the mrna
codon
45
which rna forms part of the ribosome ?
ribosomal
46
which rna synthesise proteins ?
rrna
47
ribosomes of euaryotic are larger or smaller ?
larger
48
carrier of genetic info from dna to protein synthesis
Mrna
49
wt do we call the sequencewithin the mrna taht codes for polypeptide
ORF open reading frame
50
codes for multiple proteins ( polycistronic )? who
prokaryotic MRNA
51
CODES for only a single polypeptide and is therefore referred to as
eukaryotic MRNA , monocistronic
52
do not directly code for polypeptides
NCRNA
53
have roles in the activation or inhibiton of gene expression
regulatory RNA
54
RNA SPLICING, CHEMICAL MODIFICATIONS OF NUCLEOTIDE BASES WHO ?
house keeping NCRNAS
55